Oralight is developing a patent-protected precision photobiomodulation platform for oral mucositis, using a proprietary Optical Surface Applicator to make light therapy more consistent and measurable. Licensed from Roswell Park Comprehensive Cancer Center, the platform uses closed-loop feedback to control delivered light energy and is being developed for a pilot clinical study. Its founding team brings more than 40 years of photonics commercialization experience and multiple successful exits.
Biolectrics LLCBiolectrics LLC develops OraFlow, a personal mouthpiece designed for periodontal therapy. Based in Rocky River, Ohio, the company focuses on a smart, home-oriented approach to oral care.CLEVELAND, OH
Ortek-BasicBites®Founded in 1998, Ortek Therapeutics develops oral-health technologies and makes BasicBites, sugar-free soft chews designed to support enamel and the oral microbiome. The company’s work grew from a long-running collaboration with the Research Foundation for the State University of New York and Stony Brook University School of Dental Medicine, where its arginine bicarbonate and calcium carbonate technology was developed and clinically tested. Ortek also created the FDA-cleared Ortek-ECD device for early detection of occlusal cavities, while BasicBites brings its microbiome research into a daily consumer product manufactured in the United States at an FDA-registered, CGMP facility.ROSLYN HEIGHTS, NY
PhotoOpTxBased in Solon, Ohio, PhotoOpTx develops photobiomodulation medical devices and treatment protocols for retinal disorders, including its investigational Retilux laser therapy device for diabetic macular edema. The company’s work centers on non-pharmacological light-based approaches intended to address unmet needs in ophthalmology, with research conducted alongside organizations such as the Jaeb Center for Health Research and the DRCR Network.SOLON, OH
SunPowerLED (Kerber USA Inc.)Founded by Tom Kerber, SunPowerLED is the light-therapy operation of Kerber USA Inc., developing photobiomodulation equipment for home users, healthcare professionals, and university researchers. The Amherst company is known for engineering its devices around active cooling and spectroradiometer-verified light output, with its transcranial PBM helmet tied to a published, IRB-approved university study.AMHERST, NY