Paritic Inc. develops 3D medical-imaging software, tracking hardware and integrated navigation systems for minimally invasive procedures. Its Pari-Path system overlays tracked instruments with CT and ultrasound imagery in three-dimensional space, supporting pre-operative planning and intra-operative guidance for puncture procedures. The system was FDA-cleared in 2014 and received China medical-device certification in 2022.
FDA clearance for Pari-Path surgical navigation system
China medical device registration: navigation equipment for puncture surgery, certificate GXZJ 20223010401
Registration
FDA
Quality certification
MediView XR, IncCleveland-based MediView XR develops augmented-reality visualization and navigation systems that give clinicians a real-time, three-dimensional view of patient anatomy during image-guided procedures. Its platform fuses CT data with live ultrasound and supports remote collaboration, while its FDA-cleared XR90 has already been used clinically for minimally invasive navigation. The company grew from Cleveland Clinic-developed intellectual property and works with partners including GE HealthCare and Microsoft.CLEVELAND, OH
Clear Guide MedicalSpun out of Johns Hopkins and headquartered in Baltimore, Clear Guide Medical develops image-fusion and augmented-reality navigation systems for minimally invasive medical procedures. Its patented SuperPROBE platform tracks instruments directly from an ultrasound transducer, combining live ultrasound with CT or MRI guidance for procedures such as biopsies and ablations. The privately held company’s technology is supported by FDA 510(k) clearances and ISO 13485 certification.BALTIMORE, MD
Centerline BiomedicalBorn from a Cleveland Clinic collaboration, Cleveland’s Centerline Biomedical develops 3D surgical navigation technology for endovascular procedures. Founded in 2014, the company’s FDA-cleared Intra-Operative Positioning System (IOPS®) combines patient-specific imaging with sensor-equipped catheters and guidewires to provide real-time positioning while helping reduce reliance on radiation-inducing fluoroscopy. Founder and CTO Vikash Goel and his team developed the technology through a decade of work with Cleveland Clinic vascular surgeon Dr. Roy Greenberg.CLEVELAND, OH
PAR Excellence Systems, IncFounded in Cincinnati in 1993, PAR Excellence Systems develops healthcare supply-chain systems that pair proprietary hardware with cloud software for real-time inventory visibility and operational control. The company is known for pioneering weight-based inventory management and, following its 2025 combination with TrackCore, also provides automated tracking for surgical tissues and implants. PAR’s platform supports more than 1,700 clients and manages $2 billion in healthcare inventory.CINCINNATI, OH