Founded by Harold Meckler and Karl Popp in 2014, Pharmapotheca A develops pharmaceutical chemistry technologies and supplies patent-protected compounds for chemical and pharmaceutical research. The Delmar company focuses on amphetamine-related synthesis, controlled-release and abuse-deterrent dosage-form technologies, with its intellectual property exclusively licensed in part from Chemapotheca. In 2020, synthetic organic chemist Thomas E. D’Ambra joined as CEO to guide the company’s expansion.
Chem-Master International, IncFounded in 1994, Chem-Master International is a privately held Hauppauge research, development and manufacturing company that provides contract work in organic and medicinal chemistry. Its scientist-owned team includes 14 full-time Ph.D. scientists and draws on 75 years of combined industrial and academic research experience. Operating from a 2,000-square-foot laboratory associated with Stony Brook University’s Long Island High Technology Incubator, the company develops custom compounds and scalable chemical processes for pharmaceutical, biotechnology and academic clients.HAUPPAUGE, NY
Syntho Pharmaceuticals, IncFounded in 1999 by pharmacist Muhammed Malik and Hosneara Malik, Syntho Pharmaceuticals is a family-run Farmingdale manufacturer developing and producing branded and generic medicines. Now led by Hosneara as president and their daughter Tithi in operations and regulatory management, the company combines in-house analytical testing with FDA-registered, DEA Schedule CIII–CV licensed manufacturing and packaging capabilities. Its team works across development, quality, production, and regulatory support for pharmaceutical clients.FARMINGDALE, NY
Pharmaceutical Manufacturing Research Services, Inc. (PMRS)Founded by Edwin R. Thompson in 1994, privately held PMRS develops and contract-manufactures pharmaceutical products from clinical supply through commercial production, with analytical and quality support under one roof. The Horsham company has grown from six employees to about 30 and has completed more than 550 projects, supporting four NDA-approved commercial products, an internationally approved product, and developmental drugs. Its 130,000-square-foot custom facility and hands-on, cross-functional staff reflect a model in which every team member is involved in each project.HORSHAM, PA
AstaTech, IncFounded in 1996 by former pharmaceutical-company scientists, Bristol, Pennsylvania-based AstaTech develops and manufactures drug-discovery building blocks and advanced intermediates while providing chemistry CRO/CDMO services. Its in-house team includes PhD chemists, and the company supports projects from discovery through commercial-scale manufacturing for 1,000 companies worldwide. AstaTech’s catalog includes more than 250,000 compounds, with custom synthesis available from milligram quantities through 10 kilograms and bulk manufacturing extending to ton scales.BRISTOL, PA