Founded in 2007, Physical Pharmaceutica is a specialist pharmaceutical R&D firm built around the cross-disciplinary work of founding partner Robert A. Bellantone, a physicist who is also a registered pharmacist. The company develops tailored experimental and computational approaches for pharmaceutical companies and the FDA when standard methods fail, with particular recognition for its patented work supporting complex ophthalmic products.
Pine PharmaceuticalsFounded in 2014 by father and son Alfonse Muto and Alfonse J. Muto, Pine Pharmaceuticals is an independently owned FDA-registered 503B outsourcing facility that prepares compounded and repackaged drugs for hospitals, surgery centers, and specialty practices. From its 75,000-square-foot facility, the company distributes millions of ready-to-use units each year, with a particular focus on ophthalmic products and hospital supply needs. Pine’s roots reach back to local compounding pharmacies dating to 1985, and its operations follow cGMP standards with on-campus quality-control testing.TONAWANDA, NY
Pharmaceutics International, Inc. (Pii)Founded in 1994, Pharmaceutics International, Inc. (Pii) is a Hunt Valley drug product contract development and manufacturing organization that takes pharmaceutical products from early development through clinical trials and commercial production. Now part of Jabil, Pii combines more than 30 years of complex-formulation experience with a 360,000-square-foot, four-site campus and more than 300 scientists and support staff. Its GMP facilities are built for demanding work, including potent compounds, complex injectables and oral drug products, with FDA-licensed and DEA-registered operations.HUNT VALLEY, MD
Sigmapharm Laboratories, LLCFounded by Dr. Spiro Spireas in 2005, Sigmapharm Laboratories is a privately held specialty pharmaceutical company built around solving formulation problems that make certain medicines difficult to develop. From its Bensalem campus, the company researches and manufactures generic and branded drugs using proprietary delivery systems, then brings selected products to market under its own label.BENSALEM, PA
Pharmapotheca A, IncFounded by Harold Meckler and Karl Popp in 2014, Pharmapotheca A develops pharmaceutical chemistry technologies and supplies patent-protected compounds for chemical and pharmaceutical research. The Delmar company focuses on amphetamine-related synthesis, controlled-release and abuse-deterrent dosage-form technologies, with its intellectual property exclusively licensed in part from Chemapotheca. In 2020, synthetic organic chemist Thomas E. D’Ambra joined as CEO to guide the company’s expansion.DELMAR, NY