Remedy Pharmaceuticals, Inc. develops CIRARA, an investigational drug aimed at helping patients recover from major strokes. The company’s work is illustrated by its Phase 2 clinical trial at Yale New Haven Hospital, where survivor Jaclyn received CIRARA after suffering a massive stroke in 2015 and reports doing well a decade later. Remedy also operates through Remedy Pharmaceuticals Pty Ltd, a wholly owned Australian subsidiary.
Hybernia Medical, INCFounded and managed since 2006 by physicians and inventors, Hybernia Medical develops endovascular medical technology for selectively cooling the brain during acute ischemic stroke treatment. The Mineola company’s patented Delta-H Cooling Technology is designed to deliver rapid, controlled hypothermic protection through the same arterial access used for endovascular stroke care. Originally spun off from Columbia University, Hybernia is a clinical-development-stage company whose technology has advanced from bench engineering to preclinical testing and a first-in-human study.UNIONDALE, NY
SERB PharmaceuticalsSERB Pharmaceuticals develops, manufactures, and supplies specialist medicines for rare diseases and medical emergencies, with a particular strength in antidotes and other critical-care treatments. Beginning in the 1950s as Société d’Études et de Recherches Biologiques, the company now supplies more than 70 medicines through direct operations and distribution partners in over 100 countries. Its fully integrated platform includes a commercial-scale polyclonal antibody manufacturing capability and four manufacturing facilities across three continents.325412CONSHOHOCKEN, PA
Braeburn IncPlymouth Meeting-based Braeburn develops specialty pharmaceutical treatments for opioid use disorder, including BRIXADI, a buprenorphine extended-release injection. Its work extends beyond drug development into research, advocacy and community partnerships aimed at reducing stigma and improving access to recovery care, with particular attention to underserved populations.325412PLYMOUTH MEETING, PA
PGRrxPGRrx is a 503B pharmaceutical outsourcing facility that produces sterile and non-sterile compounded medicines to help healthcare providers navigate drug shortages and tailor dosage forms to patient needs. Founded by pharmacist Amit Gupta, the company also supports CMC and clinical-trial research, drawing on his experience leading sterile and non-sterile compounding in inpatient institutions. Its work is organized around supplying safe, personalized pharmaceutical access to communities facing gaps in availability.EXTON, PA