Founded in 2016 through a collaboration between UMBC engineering researchers and Johns Hopkins sleep physicians, Tanzen Medical develops remote-monitoring technology for diagnosing and managing sleep movement disorders. Its RestEaze system combines an ankle-worn sensor, mobile app, and cloud analytics to characterize leg movements across multiple nights at home rather than relying only on a single in-lab study. Tanzen has received FDA Breakthrough Device Designation for RestEaze and has sold the system in limited quantities for sleep research.
FDA Breakthrough Device Designation
Compliance program
Ambulatory Monitoring, Inc. (AMI)Founded by William Gruen, Ambulatory Monitoring, Inc. (AMI) makes FDA-registered medical devices for long-term monitoring of sleep, activity, vigilance, respiration and other physiological functions in people moving through their everyday environments. For more than 35 years, its Motionlogger actigraphs have been used in clinical and research settings, while its equipment has traveled from medical clinics and NASA missions to the ocean floor and Mount Everest. AMI is now managed by President Thomas Kazlausky, a former vice president and product manager, alongside Vice President Linda Tavolacci, who has worked with the company for nearly 30 years.ARDSLEY, NY
DormotechDormotech develops wireless hardware, clinical software, and cloud infrastructure for comprehensive sleep diagnostics in both patients’ homes and attended laboratories. Its DormoVision X™ platform connects 38-channel home and in-lab polysomnography within one review and reporting workspace, with the company reporting 96.6% agreement with traditional attended Type I PSG in clinical validation. Dormotech also offers a research platform for multichannel sleep data and machine-learning analysis.YOUNGSTOWN, OH
General Sleep CorporationEstablished in Cleveland in 1992, General Sleep Corporation is a medical-device developer known for applying EEG to the study of sleep and sleep disorders. Its Zmachine technology supports clinical and research work, including at-home monitoring, for licensed healthcare and research professionals rather than patients directly. The company holds patents related to insomnia treatment, brainwave analysis, and signal processing.CLEVELAND, OH
BTE TechnologiesBTE Technologies traces its history to 1979, when its founders introduced what the company describes as the first device for objectively measuring movement while simulating real-world tasks in rehabilitation. Today, the Hanover, Maryland, medical device company develops technology for occupational and physical therapists who need functional treatment and evaluation backed by measurable clinical data. BTE is ISO 13485:2016 registered.HANOVER, MD