Founded in 1999, Sparks-based TrimGen Corporation develops genetic testing products and proprietary molecular technologies for clinical research and early disease detection. Its work includes the patented Shifted Termination Assay for sensitive mutation analysis and WaxFree extraction technology, which is designed to recover nucleic acids from limited FFPE and FNA tissue. TrimGen says its products are used by clinical laboratories globally and have been cited in hundreds of academic publications.
FDA 510(k) quality assured reagents
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MiTeGen, LLCFounded in 2004 by Cornell Professor Robert Thorne, Ithaca-based MiTeGen is a scientific tools company built around translating physics into practical solutions for researchers. It works with laboratories in more than 40 countries, developing and supplying specialized equipment for structural research while also taking on custom projects shaped by a researcher’s specific needs.ITHACA, NY
OraSure Technologies, IncFounded in 1987 as SolarCare in Bethlehem, OraSure Technologies develops and manufactures non-invasive rapid diagnostic tests and biological-sample collection devices. Now headquartered in Bethlehem and publicly traded since 2000, the company is known for point-of-care testing that brings HIV, HCV and other infectious-disease results closer to patients, alongside DNA Genotek sample-management solutions for genomic and microbiome research. Its OraQuick platform includes the first FDA-approved, CLIA-waived rapid HCV test and an oral-fluid HIV self-test.325413BETHLEHEM, PA
OriGene Technologies, IncFounded in 1996, Rockville-based OriGene Technologies develops genomic and proteomic research tools, anchored by a proprietary collection of more than 586,000 full-length human cDNA clones. Its catalog now exceeds one million products, while custom work runs from gene cloning through protein purification and includes antibody specificity testing using high-density protein microarrays. OriGene also manufactures custom proteins in the United States and serves researchers worldwide.ROCKVILLE, MD
Akonni Biosystems, IncA Frederick, Maryland molecular diagnostics company, Akonni Biosystems is known for building integrated tools that help laboratories extract and analyze genetic material. Its nearly 20,000-square-foot manufacturing facility sits near Fort Detrick, the NIH and the National Cancer Institute, and its work includes the TruTip system for streamlined nucleic-acid preparation. Akonni develops these products for clinical diagnostics and research laboratories seeking practical, high-throughput testing workflows.FREDERICK, MD