Trufacial is a skincare company based in Wayne, Pennsylvania, known for bringing professional-style facial care into the home. Its patented device is designed for people seeking a brief, repeatable treatment, using exfoliation and serum infusion to refresh the skin.
FrowniesBorn from a mother-daughter invention in 1889, Frownies makes its signature facial patches along with complementary skincare designed to smooth and care for expression-prone skin. The woman-owned company remains in its fifth generation, and its Dayton, Ohio team handcrafts small batches of products such as its Bulgarian rose hydrosol spray. Frownies’ original patches use a water-activated adhesive that hardens to hold skin relaxed and flat, a distinctive approach the brand says predates injectable wrinkle treatments.DAYTON, OH
WrinkleMD Skincare & Technologies IncFounded in Bel Air, Maryland, WrinkleMD Skincare & Technologies Inc. makes at-home anti-aging infusion systems that use a Micro-Pulse Ion Activator Pod to deliver medical-grade hyaluronic acid through targeted patches. Developed with dermatologists and aesthetic experts after the team’s experience in aesthetic medicine, the company brings clinic-inspired delivery to a weekly home ritual, with clinical testing reporting up to 15-times deeper HA delivery and visible improvement within eight weeks.BETHESDA, MD
The Skin Care SourceThe Skin Care Source is a Pennsylvania skincare company whose management team brings more than 40 years of experience from established beauty firms. It creates and manufactures clinical skincare formulas for private-label brands, using a patented delivery system and declining animal testing of any kind.EAST NORRITON, PA
PROMEDAFF SKIN CARE, INCPROMEDAFF SKIN CARE, INC. develops and markets naturally derived cosmetics and skin-care products aimed at preventing, improving, or treating a range of skin conditions. Based in Chadds Ford, Pennsylvania, the company offers products such as its AcSCANEX acne-and-scar serum and BARRONN age-defying serum, with a stated focus on safe use across all skin types.CHADDS FORD, PA