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With a 120-year history, Irwin Car and Equipment is a Pennsylvania manufacturer known for solving demanding material-handling problems for heavy industry. The company supports customers with custom equipment and rebuild work, drawing on multiple U.S. manufacturing locations and nearly 300 years of combined engineering, manufacturing and design experience in its rail-products group.
Irwin Car and Equipment engineers and manufactures custom locomotives, rail equipment, heavy-duty material handling equipment, transit components, and industrial handling products. Its capabilities include metalworking, fabrication, machining, welding, plasma spray, powder coating, finishing, component assembly, reverse engineering, repair, rebuilding, and testing for metals, mining, tunneling, energy, transportation, transit, rail, and other heavy industrial markets.
Irwin Car and Equipment is a heavy-duty material handling equipment leader, manufacturing custom locomotives, rail cars, and traction motor services for mining, tunneling, energy, and transportation industries.
Since 1922, Cleveland’s Irwin Engraving and Printing Co. has preserved the craft of fine engraving while producing distinctive printed pieces for clients near and far. Milan Nass took over in 1965, and his sons David and Dan now carry on the family business as master engravers with more than 50 years of combined experience. From a 15,000-square-foot Cleveland plant, the company pairs traditional, hands-on workmanship with modern printing technology and takes on both highly customized projects and short runs.
Founded by Dr. Anthony Sterns after a decade researching dementia care, Akron-based iRx Reminder develops medication-management technology that helps patients take the right dose at the right time while keeping healthcare teams informed. Its platform pairs a cloud control center and patient apps with the iLidRx dispensing pod, which uses a simple “Hold, Place, and Tilt” motion and reports dispensing in near real time. The company’s system is used in behavioral health, pharmacies, and clinical research, with 19 customers reported using the platform and collaborations spanning institutions including the University of Michigan Cancer Center.
Founded by Isaac Mizrahi in 1987, the New York fashion brand creates women’s clothing and eyewear built around classic, clean silhouettes with exuberant color and pattern. Its accessible fashion approach gained broad attention through the Isaac Mizrahi for Target collaboration, while the designer’s work has earned four Council of Fashion Designers of America awards.
Born from a scrap-trading concern started in 1940, ISC Group manufactures lifting magnets and related material-handling equipment for iron, steel and scrap operations. The Singh family has spent more than 40 years studying and using magnets in its own steel plants and scrap yards, experience reflected in equipment for applications from furnace charging to large-scale scrap handling. Based in Kolkata, ISC also repairs and re-engineers magnetic equipment of different makes, types and sizes in its own workshop.
With an engineering division behind it, ISCA Hygienic Processing Solutions supplies new and used equipment for meat, bakery and broader food-production operations. The Bethesda-based company also manufactures ISCA-branded ancillary equipment and refurbishes or customizes machinery to fit a customer’s requirements, with a team bringing more than 200 years of combined food-manufacturing experience.
ISCO Industries is a family-owned Louisville piping-solutions business founded in 1962, initially supplying underground golf-course irrigation materials before specializing in HDPE. It supplies piping products and fusion equipment and fabricates custom HDPE structures and assemblies. The company describes itself as a global provider with more than 35 facilities across the United States and Canada.
Opened in 2013 after Isel Germany acquired Techno Inc.’s assets and customer list, Isel USA serves as Isel Germany’s North American stocking distributor for linear motion and industrial automation equipment. The Hicksville, New York company supports customers in the United States, Canada and Mexico with German-made components and configurable automation systems, while its engineers assist with compatibility questions and custom OEM designs. Isel USA’s broader group traces its roots to 1972, and its products have supported precision automation applications since 1986.
Based in East Rochester, iSell Packaging manufactures custom retail, food, industrial and security bags, with U.S. production supplemented by overseas factories. Its specialty is tailoring packaging to demanding workflows, from SECUR-PAK patient-value bags and tamper-evident casino packaging to FDA-approved food bags, while providing in-house graphic arts support and a detailed pre-press proof before production. The company’s team includes a package designer with more than 30 years of hands-on experience and has served healthcare, retail, financial, correctional and other industries.
ISG Health provides FDA approved PPE products such as masks, gloves, and gowns. The company states all products are in stock and ready for immediate delivery.
Founded in 1981, iSheaves designs and manufactures stock and custom sheaves and pulleys for wire-rope and cable applications. Based in Paterson’s historic Watson Building, a metal-fabrication site dating to 1860, the company supplies sizes from 4 to 48 inches and is especially known for pioneering cast-nylon sheaves for the wire and cable industry. iSheaves also duplicates broken or obsolete sheaves from samples, drawings, or reverse-engineered specifications.
ISI Services Corp. is a New Rochelle insignia supplier known for work made for public-safety and military organizations. The company is an authorized vendor of United States Marshal Service insignia and an authorized distributor of Smith & Warren badges, creating custom designs from existing patches or rough sketches.
Founded from a shared insight between an anaesthetist and an intensive-care paramedic, iSimulate develops mobile clinical-education technology for realistic healthcare simulation. Launched in 2011 with an iPad-based ALS training system, the company now builds portable systems that can reproduce patient monitors, defibrillators and fetal heart-rate monitoring for training outside traditional simulation centres. iSimulate became part of the 3B Scientific Group in 2020 and continues to operate from Canberra, Australia, and Albany, New York.
Incorporated in 1991, iSine is a fabless semiconductor design house that develops and delivers custom analog, digital and mixed-signal ASICs from specification through packaged, tested production. The small engineering team is particularly experienced in combining high-voltage analog with low-voltage digital circuitry and in redesigning obsolete integrated circuits for newer manufacturing processes. iSine also makes standard lighting drivers and power-management products, including an ACCEL™ regulator used in the EVLA radio telescope.
ISK Animal Health develops animal-health medicines, including BRENDA™, a treatment for reducing clinical signs associated with acute pancreatitis in dogs. Its fuzapladib sodium hydrate works through a distinct mechanism that blocks inflammatory-cell adhesion, and the product received manufacturing and marketing approval in Japan in 2018.
Founded in 1975, ISL Products International designs and manufactures electromechanical components for OEMs, with particular depth in DC motors and gear motors. From its Melville, New York headquarters, the company pairs standard components with application-specific engineering and can re-engineer obsolete parts through its Continuous Source Manufacturing program. ISL supports customers globally with a 1M-plus-square-foot warehouse network and serves more than 500 OEM customers.
Since 1971, Island Automated Gate Systems has built its reputation serving top builders, government agencies and management companies with customized automated gate systems. The Huntington Station company works closely with designers and landscape architects, handling projects from design through installation while also repairing older systems for residential and commercial customers.
Since joining G.W. Lisk Company in 2021, Island Components Group has operated independently as a Hauppauge precision-motion manufacturer with more than 25 years of experience supporting space missions. The company is known for developing mission-critical motors and servo-actuators for aerospace, defense and space customers, including Workhorse Actuators selected for NASA’s Mars Sample Return program.