Manufacturer Directory
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MD
Optimum Labs LLC manufactures upper-extremity prosthetic devices, custom rolled silicone liners, and fabrication tools for the clinicians who build them. Its work combines custom CAD and 3D-printed cores with silicone fabrication, while its small equipment line includes practical solutions such as the BubbleUP plaster degassing tool and adjustable prosthetic components. The company also offers digital fabrication files and says custom fabrication typically takes two to three weeks.
Founded in 2019, Optosurgical is a Columbia, Maryland startup developing surgical-vision technology for clinicians working in minimally invasive procedures. Its research centers on making critical anatomy visible in real time, including through the hANDY-i system for parathyroid visualization. The company’s work has received NIH and ARPA-H SBIR Phase II support and is being developed with clinical partners including Johns Hopkins Hospital.
Orano’s Kevil, Kentucky facility is known for specialized freight forwarding for the nuclear industry, moving radioactive cargo for customers across the front and back ends of the fuel cycle. The site also operates a cylinder service center and supports licensed packaging work under an NRC-approved NQA-1 quality program.
Established in 1984, Orca, Inc. is a Connecticut manufacturer known for more than 35 years of specialized work in rigid metal packaging. Its Unitop utility cans serve industrial and chemical applications, with order quantities ranging from a single carton to multi-truckload and rail shipments.
Woman-owned and family-operated in Middletown, Maryland, Orchid Cellar Meadery and Winery crafts mead and wine, bringing the world’s oldest alcoholic drink into a modern setting. Its locally made beverages have earned international awards while building a distinctive Maryland identity.
Founded in 1996, Rockville-based OriGene Technologies develops genomic and proteomic research tools, anchored by a proprietary collection of more than 586,000 full-length human cDNA clones. Its catalog now exceeds one million products, while custom work runs from gene cloning through protein purification and includes antibody specificity testing using high-density protein microarrays. OriGene also manufactures custom proteins in the United States and serves researchers worldwide.
Four generations after Leonardo Alarcon began working with coffee beans in southwest Venezuela, Orinoco Coffee & Tea remains a family-rooted roasting company with its home in Maryland. Its work carries a 1909 heritage into custom-roasted coffee and premium tea for retailers, coffee shops, and grocery chains across the United States.
With nearly a century of flare-making behind it, Orion Safety Products manufactures emergency flares and signaling devices for roads, waterways, homes, and the outdoors. Its products are engineered and made in the USA at facilities in Indiana and Pennsylvania, while corporate headquarters are in Easton, Maryland. Orion is particularly rooted in marine distress signaling, producing USCG-approved visual distress signals and SOLAS-approved products, and its highway and railway flares are made to UL 912 specifications.
Family-owned and operated since 1992, Orlando Products Inc. has built its Baltimore operation around solving demanding packaging challenges for customers in fields such as aerospace, military, and medical equipment. Its 150,000-plus-square-foot facility houses an in-house engineering team with more than 60 years of combined industry experience, supporting custom packaging work from design through production. The company also runs a recycling program that reuses foam scrap and incorporates recycled material where possible.
As a veteran-owned small business with more than 20 years serving the Washington, DC, and Baltimore metro areas, Orthocare Solutions is known for individualized patient care across four locations. Its clinicians create customized orthotics for patients of all ages and also support hospitals and government healthcare programs with on-site fitting services. The company is certified as a Veteran-Owned Small Business and Minority Business Enterprise, with BOC and ABCOP-accredited practitioners and facilities.
Founded in 2011 through a collaboration between Uppsala University and Karolinska University, OssDsign AB develops and supplies orthobiologics that support bone healing. The Uppsala company now focuses solely on OssDsign Catalyst®, a nanosynthetic, silicate-substituted bone graft substitute designed for spinal fusion and other bone-healing applications. OssDsign became a pure-play orthobiologics company in 2024 after discontinuing its cranial implant business.
Otomagnetics is developing a magnetic injection drug-delivery platform that uses a proprietary magnetic device and biodegradable particles to move therapies non-invasively into hard-to-reach ear and eye tissues. Founded by hearing and neuroscience researcher Didier Depireux, the Gaithersburg company has demonstrated delivery to inner- and middle-ear compartments in animal models, including middle-ear delivery without puncturing the eardrum. Its multidisciplinary team includes CEO Abhita Batra and Chief Medical Officer Karen Stierman, an otolaryngologist with an electrical-engineering background.
Since 1881, Otterbein’s Cookies has baked thin, crispy cookies in Maryland, preserving the signature crunch that began with the Otterbein family’s original recipe. The company still uses that same style of bake and, for its sugar cookies, a deliberately simple six-ingredient formula that has made Otterbein’s a Baltimore-area staple for generations.
Since 1881, Otterbein’s Cookies has baked Maryland’s signature thin-and-crispy cookies, using the same original recipe and method that made the brand a regional staple. The family’s six-ingredient sugar cookie and unmistakable paper-thin crunch remain central to a Maryland tradition now more than 140 years old.
Oversea Distillery brings traditional Chinese baijiu together with American whiskey-making in a Columbia, Maryland, distillery and bar. Its signature distinction is a light-aroma baijiu crafted and aged on U.S. soil, alongside a baijiu aged in China and finished for another year in the distillery’s used whiskey barrels. The venue pairs house-distilled spirits with globally influenced cocktails, food, live entertainment, and flexible event space.
Established in 1999, Owl Cyber Defense Solutions is a Columbia, Maryland cybersecurity company known for pioneering commercial data diode technology and building it in the United States. Its security systems help government and critical-infrastructure organizations move sensitive information across network boundaries, and the company reports deployments in more than 90% of U.S. nuclear power plants.
Founded in 1974, P.F. Industries Inc. in Saint-Martin, Quebec, turns locally sourced spruce and fir into fence components, bed-frame parts and precision-cut lumber for manufacturers. Its 40 years of experience include assembling fence panels and developing specialized wood components, while its employee survey reflects a workplace built around training, advancement and work-life balance.
Founded in 1993 as a small research-and-development company, Hagerstown’s P&D Creative Co., Inc. formulates and manufactures non-toxic, biodegradable cleaning products for industrial, institutional and household use. Its Magic 555, MotorPro and Effective brands grew from an early colloidal-chemistry stain remover into a broader cleaning line, while the company also develops custom formulations and private-label products. P&D Creative is an SBA-certified 8(a) small manufacturing and services company and a two-time GSA Multiple Award Schedule contractor serving government customers.
Founded in 2022 by Michael Pace, Pacesetter Signs and Graphics is an Elkton, Maryland company shaped by its owner’s background in graphic design and more than 15 years in corporate product and project management. Pace built the business around working directly with local entrepreneurs and helping them turn their brand into clear, custom signage, with projects carried from design through installation.
Formed by packaging enthusiasts and innovative designers, Pack Arena is a custom packaging company built around helping brands turn product concepts into practical, polished packages. It supports businesses with design guidance and flexible order quantities, producing packaging for retail and e-commerce products.