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Launched in 2001, Lansing-based NovaSterilis develops supercritical CO2 terminal-sterilization processes, equipment, and testing services for sensitive medical products and materials. Its patented Nova Process was commercialized in 2007, and tissue sterilized through the process has been used in more than 500,000 surgeries worldwide. The company combines engineering and life-science expertise to help customers assess compatibility, develop processes, and move scCO2 solutions toward production and regulatory clearance.
From its Baltimore base, Novatec, Inc. manufactures resin-drying and plastics-conveying equipment and integrated material-handling systems for plastics processors. The American-owned, American-made company has more than 75 years in the industry and operates a Drying Technology Center where customer resin samples can be tested against competing dryer technologies. Its partnership with Maguire Products extends its offering into a broader range of plastics auxiliary equipment, while AI-enabled moisture management and conveying technologies add a newer layer to its established equipment expertise.
NovaTech Automation is a U.S.-based manufacturer of automation, control, and communication products for electric utilities and process manufacturers. Founded in 1979, the privately owned, veteran-led company designs and manufactures its products in the United States and supports customers worldwide through field offices and regional partners. Its work centers on helping operators automate and manage power-grid infrastructure while extending the service life of legacy equipment.
Founded by Alfonse Novelli in 2002, Bethlehem-based Novation Inc. designs and manufactures automatic web-flagging and defect-tracking equipment for printers and converters. Its WebFlagger systems mark defects on fast-moving webs without putting operators near moving machinery, while its ScrapTracker software records each defect’s location for later processing. Novation says its equipment is made in the USA and has more than 1,500 installations worldwide, marking over 50 million defects.
NovationSi is a Barberton, Ohio silicone specialist known for applying decades of experience to custom formulations for processors, mixers, and fabricators. Its PURmix® compounds extend silicone into electrically conductive applications, including medical-device designs, while the company also provides color-matching support for silicone manufacturers.
Headquartered in Gaithersburg, Maryland, Novavax is a biotech company that develops vaccines and vaccine technologies, pairing protein-based nanoparticles with its proprietary Matrix-M® adjuvant. Its platform underpins marketed vaccines for COVID-19 and malaria, while the company continues in-house R&D and works with pharmaceutical, research and government partners to advance additional medicines. Novavax also conducts R&D and Matrix-M manufacturing in Uppsala, Sweden.
Founded in 1994 as a hologram research-and-development company, Bowling Green’s NovaVision manufactures anti-tampering and anti-counterfeiting products, including holographic security labels and tamper-evident tape. The company serves customers globally from a 47,000-square-foot production operation and additional U.S. sites, with 170 full-time employees. NovaVision’s security-focused manufacturing is backed by ISO 9001:2015, ISO 14298:2015 and ISO 14001:2015 certifications, along with CTPAT certification at its Bowling Green facility.
Since 1997, NOVAWINCH has designed and manufactured winches and hoists, including equipment built for demanding industrial and vehicle applications. The company says it built China’s first complete winch and has produced more than 4 million winches, using a modern facility with robotics, laser measurement and robotic welding. Its engineering and manufacturing systems are certified to ISO 9001, ISO 14001 and IATF 16949 standards.
Family-owned Novel Box Company, Ltd. has been making jewelry packaging and display products from its Brooklyn, New York shop since 1949. Its assortment includes distinctive presentation pieces such as built-in LED jewelry boxes, while the company also handles custom orders, hot stamping, and manufacturing from customer samples. Most products are made in the USA, and stock orders are typically turned around within 24 hours.
Serving North America since 1987, Pittsburgh-based novel electronics inc. is known for applying calibrated sensor technology to precise load-distribution measurement. The company works with novel gmbh of Munich to support researchers, clinicians, universities and industrial customers, with its systems notably used in a NASA International Space Station treadmill study.
Founded in Munich in 1978, novel GmbH develops calibrated sensor systems that measure pressure and force where surfaces meet—from the foot inside a shoe to a hand on a tool or a body on a seat. The company remains relatively small and highly specialized, with its systems used in medical practice, biomechanics, industrial development and research worldwide. Its measurement technology is managed under ISO 13485-based quality processes and is supported by scientific software, custom development and training.
Baltimore-based Novel Microdevices develops portable, sample-to-answer molecular diagnostic systems built around disposable microfluidic cartridges. Its battery-powered Novel Dx platform is designed to deliver lab-quality PCR results in about 15 minutes, including testing for respiratory infections and other diseases at the point of care. The company is establishing a GMP-compliant pilot manufacturing facility at its Baltimore headquarters to scale cartridge production.
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Novele is an energy technology company whose team brings together expertise in battery systems, electrical engineering, software, and applied artificial intelligence. It develops energy-control solutions for buildings and data centers, including RippleBoard for adaptable rack-level power management and BoardOS for real-time energy intelligence.
Novelis produces low-carbon flat-rolled aluminum products and is the world’s largest aluminum recycler. Its integrated network of rolling and recycling facilities spans four continents, supplying aluminum sheet to customers in aerospace, automotive, beverage packaging and specialty markets. The company says it recycles more than 85 billion beverage cans each year and is a subsidiary of Hindalco Industries Limited.
Since 1911, Lancaster-based Novelty Manufacturing Co. has grown from a small trinket maker into an American manufacturer of plastic consumer goods, including gardening products and home-improvement solutions. Its NMC Contract Molding operation also helps customers take plastic products from industrial design and pre-production through molding, assembly, and distribution. The company’s long history includes the Countryside planter line, developed by Melinda Winger and her father in the early 1990s.
Noveome Biotherapeutics is a Pittsburgh-based clinical-stage biopharmaceutical company developing ST266, a non-cellular biologic derived from the secretome of cultured amnion-derived epithelial cells. Its scalable GMP process produces the investigational biologic for research and clinical development across challenging diseases and conditions, with the company describing activity in clinical and preclinical studies.
Born from B.F. Goodrich’s Novitane line, Novex has been an Ohio polyurethane manufacturer since 1987, serving industrial customers around the world. The company moved into a Barberton facility in 2024, doubling its operating capacity while continuing its focus on durable materials for demanding applications.
Novex Products is a growing Lorain, Ohio manufacturer serving paper distributors, supply houses, and retail customers. It also handles private-label work for large orders, tailoring paper products to customer specifications.
Born from the 2010 merger of two northeast Ohio businesses—Laser Printing Solutions, founded in 1994, and Wheeler Publishing, founded in 1991—Novex Systems brings their combined experience to custom warehouse identification work. The company is known for using specialized database techniques in variable-data printing, turning client information into labels tailored to demanding warehouse environments. Its work serves operations that need durable, data-driven identification, particularly in cold storage and freezer facilities.
Novinc Engineering LLC designs machines, production processes, and mechanical components, taking projects from concept through in-house prototyping and turnkey fabrication. Its work spans high-speed packaging and web-converting equipment as well as heavy industrial projects such as crane layouts and rigging plans. The company also reverse-engineers obsolete plastic parts and recreates them through 3D printing, while coordinating fabrication through a network of partner shops.