Incorporated in Delaware in late 2008, Cleveland-based Akrotome Imaging develops fluorescent molecular probes that help surgeons see cancer and its margins during resection. Its patented FIRE platform uses quenched probes that activate when they encounter tumor-associated enzymes, with the flexibility to be applied in the operating room and used alongside a near-infrared imaging system. The company’s current team has been in place since 2012 and is translating the technology toward breast and non-melanoma skin cancer applications.
Akrotome Conflict of Interest Policy Applicable to a Subaward Issued Under a Public Health Services Prime Award
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Clear Image TechnologyClear Image Technology develops direct-visualization medical imaging systems, including the portable C Scope® 2.2mm single-use arthroscope, from its base in Westlake, Ohio. The company says more than 10 years of work in medical imaging led to its modular hardware and software platform, designed to give physicians real-time views during diagnosis and treatment. Its systems are aimed at making needle arthroscopy more accessible across offices, procedure rooms, surgery centers, and operating rooms.WESTLAKE, OH
BioInVision IncFounded by biomedical imaging expert David Wilson, PhD, BioInVision is a Cleveland company built around technology developed with Case Western Reserve University. Its CryoViz™ platform helps biotechnology and pre-clinical researchers examine whole mice or organs in three dimensions at microscopic resolution, while the company also applies its imaging expertise to clinical cardiac software.CLEVELAND, OH
Ultrasonic Medical Mapping, IncBethesda-based Ultrasonic Medical Mapping develops radiation-free cancer-detection technology, adapting a mature method from defense and aerospace testing for medical use. Its patented system is focused on finding pancreatic tumors earlier and at smaller sizes than existing imaging and non-imaging technologies, and the company has built a preclinical prototype for technical validation. UMM is now working toward clinical testing with hospital and clinical partners.BETHESDA, MD
Centerline BiomedicalBorn from a Cleveland Clinic collaboration, Cleveland’s Centerline Biomedical develops 3D surgical navigation technology for endovascular procedures. Founded in 2014, the company’s FDA-cleared Intra-Operative Positioning System (IOPS®) combines patient-specific imaging with sensor-equipped catheters and guidewires to provide real-time positioning while helping reduce reliance on radiation-inducing fluoroscopy. Founder and CTO Vikash Goel and his team developed the technology through a decade of work with Cleveland Clinic vascular surgeon Dr. Roy Greenberg.CLEVELAND, OH