Founded by cryomedicine researcher John M. Baust, Ph.D., CPSI Biotech is an Owego technology-development company creating investigational cryo-medical devices and life-science research products. Its work combines cryobiology with medical-device engineering for applications in cancer treatment, cardiovascular care, and cell-therapy bioprocessing. CPSI’s pipeline includes more than 10 prototype devices, which it advances toward commercialization through partnerships, licensing, and contract research.
Kubanda CryotherapyFounded by biomedical engineers from Johns Hopkins, Baltimore-based Kubanda Cryotherapy develops cryoablation technology for minimally invasive treatment of tumors in pets. Its point-of-care system uses a cryoprobe and gas-control module to freeze unwanted tissue as an alternative to surgical resection, and the company supports veterinary practices with clinical research and education.BALTIMORE, MD
CryoConcepts, LPCryoConcepts is an Easton-based cryotherapy company founded in 1991 to bring new technology to a field that had seen little innovation for decades. Its team draws on more than 80 years of combined experience and is known for developing FDA-cleared cryosurgical solutions, including the Histofreezer system, for professional and at-home use worldwide.EASTON, PA
Cryothermic SystemsFounded in 2008 in Cleveland, Ohio, Cryothermic Systems develops medical devices that cool the body rapidly and noninvasively, led by its Cryo Cooling System for targeted temperature management. Its activated cooling packs reach -5°C in seconds and are designed to start cooling in the field before patients reach emergency, cardiac, or intensive care. The company was founded by Harvard-trained cardiothoracic surgeon Aqeel Sandhu and was formerly known as Life Core Technologies.CLEVELAND, OH
BioInVision IncFounded by biomedical imaging expert David Wilson, PhD, BioInVision is a Cleveland company built around technology developed with Case Western Reserve University. Its CryoViz™ platform helps biotechnology and pre-clinical researchers examine whole mice or organs in three dimensions at microscopic resolution, while the company also applies its imaging expertise to clinical cardiac software.CLEVELAND, OH