Marie Originals develops earth-based over-the-counter remedies, beginning with a poison ivy soap created by Oregon herbalist Marie after decades of dealing with poison oak on her 40-acre farm. Founded as a brand in 2019, the company has expanded that original urushiol-focused treatment into a broader line of natural formulas and now reaches more than 10,000 retail locations across the United States. Its research-driven approach focuses on addressing the underlying causes of everyday health concerns rather than only masking symptoms.
NAPRIM NaturalsAfter two decades as a cosmetologist, founder Stefanie Lendzian created NAPRIM Naturals to make plant-based, talc-free powders for soothing sensitive skin, scalp and hair. The Ohio-based company grew from her search for a gentler answer to her daughter’s eczema and dermatitis, and its formulas are made in the USA with organic and all-natural ingredients. NAPRIM also offers a soothing powder for pets, extending its natural-care approach across the household.
Ora K Beauty Products, LLCOra K Beauty Products makes natural, botanical hair and skin care built around a family hair-growth recipe that traces back to Freddie Mae Davis in the 1800s. Ora Kay Eatmon refined the inherited ointment into a lighter formula for all hair types, blending organic herbs, oils, and vitamins in products designed for everyone from children to people undergoing chemotherapy. The Mansfield, Ohio company says its non-toxic products are never tested on animals and typically show results within 30 to 90 days.ONTARIO, OH
MediNaturaMediNatura makes natural, homeopathic over-the-counter medicines, with a manufacturing facility in Albuquerque and headquarters in Philadelphia. Formed in 2014 after operating as the U.S. subsidiary of German homeopathic company Heel GmbH, the company is known for multi-ingredient formulas such as its T-Relief pain remedies and ReBoost cold and flu products. Its approach draws on the work of Heel founder H.H. Reckeweg and emphasizes third-party purity and potency testing.BERWYN, PA
& Tread WellFounded by sisters Emily and Claire in 2023 after returning to their family farm in New York’s Hudson Valley, & Tread Well makes 100% natural self-care for sensitive skin and senses. Drawing on backgrounds in clinical research and women’s health, the sisters formulate pared-back skincare and fragrance in small batches, blending and pouring products at their family-farm studio with plant botanicals sourced from around the globe. The brand’s dermatologist-tested, synthetic-fragrance-free approach is built around protecting the skin barrier while keeping ingredients recognizable and minimally processed.