Pittsburgh-based Neoolife, Inc. is a pre-clinical Bio-MedTech startup developing tissue-engineered biomimetic heart valves and cardiovascular patches designed to support the body’s own tissue regeneration. Its distinctive Double Component Deposition technology creates non-animal-derived polymeric scaffolds, including the OneValveTric transcatheter tricuspid valve system, while the company’s international team brings more than 130 years of combined biomedical and cardiovascular experience. The technology has received support through NIH and European Research Council grants, but Neoolife’s products remain in research and pre-clinical development and are not yet approved by regulators.
PECA LabsFounded by Carnegie Mellon alumni, including a pediatric surgeon, PECA Labs develops cardiovascular implantable devices built around a polymer platform and novel designs. The Pittsburgh company makes vascular grafts and heart-valve devices, including the radiopaque exGraft and investigational MASA Valve, whose first-in-human pediatric implant was completed in 2023. PECA Labs is ISO 13485:2016 certified.PITTSBURGH, PA
Renerva, IncFounded in 2017 out of the University of Pittsburgh and Cornell University, Pittsburgh-based Renerva develops implantable medical devices and biomaterials for peripheral nerve injury, including its investigational PNM-CAP nerve-capping device for neuroma pain. The company’s research centers on decellularized porcine nerve extracellular matrix, with products intended to help limit painful nerve growth or support nerve recovery; its technologies are not yet commercially available. Renerva operates from Pittsburgh with a satellite location in Ithaca, New York.PITTSBURGH, PA
ElutiaFounded by regenerative-medicine specialists C. Randal Mills and Michelle LeRoux Williams, Elutia develops biologic medical products that help implanted devices work more naturally with the body. Based in Gaithersburg, Maryland, the company builds on a proprietary drug-eluting biomaterial platform and engineered extracellular-matrix biology, with products for soft-tissue reconstruction and cardiovascular repair. Its SimpliDerm allograft and ProxiCor biomatrices are designed to support tissue integration and regeneration rather than simply provide inert structural support.GAITHERSBURG, MD
Intelivation TechnologiesIntelivation Technologies presents itself as an innovation hub where surgeons and engineers develop biomedical technology for orthopedic and neurosurgical care. Based in Plymouth Meeting, Pennsylvania, the company designs and commercializes implants intended to support clinical results for patients while making procedures easier for surgeons.PLYMOUTH MEETING, PA