Founded in 1999, Purgo Biologics develops oral-health biomaterials for soft-tissue and bone regeneration, including its porcine-derived THE Graft bone matrix. Its Seoul-based research and development center works with clinicians, governments, and educational institutions, while the company supplies regenerative solutions to dental professionals in more than 30 countries. Purgo says its production site is regularly inspected by international agencies, with controls covering materials through finished products.
Ortek-BasicBites®Founded in 1998, Ortek Therapeutics develops oral-health technologies and makes BasicBites, sugar-free soft chews designed to support enamel and the oral microbiome. The company’s work grew from a long-running collaboration with the Research Foundation for the State University of New York and Stony Brook University School of Dental Medicine, where its arginine bicarbonate and calcium carbonate technology was developed and clinically tested. Ortek also created the FDA-cleared Ortek-ECD device for early detection of occlusal cavities, while BasicBites brings its microbiome research into a daily consumer product manufactured in the United States at an FDA-registered, CGMP facility.ROSLYN HEIGHTS, NY
DentKist, IncDentKist, Inc. develops and produces dental materials and supplies through continuous research and development. Based in a research-driven bio-venture model, the company focuses on technology-intensive dental products and serves customers across Europe, America, and Asia.
ElutiaFounded by regenerative-medicine specialists C. Randal Mills and Michelle LeRoux Williams, Elutia develops biologic medical products that help implanted devices work more naturally with the body. Based in Gaithersburg, Maryland, the company builds on a proprietary drug-eluting biomaterial platform and engineered extracellular-matrix biology, with products for soft-tissue reconstruction and cardiovascular repair. Its SimpliDerm allograft and ProxiCor biomatrices are designed to support tissue integration and regeneration rather than simply provide inert structural support.GAITHERSBURG, MD
Per Os Biosciences LLCCreated in 2009 by a pharmaceutical industry executive, Per Os Biosciences grew from the acquisition of Koko’s Confectionery’s private-label manufacturing business. Today, its Maryland facility develops custom functional chewing gum for supplement and pharmaceutical brands, using proprietary direct-compression technology and an in-house powdered gum base.HUNT VALLEY, MD