Scientific Bioprocessing grew from Fluorometrix Corp., formed in 1999 around optical sensing patents for monitoring conditions inside living cell cultures. Now part of a history that includes Scientific Industries and aquila biolabs, the company helps bioprocess researchers replace guesswork with real-time data, particularly in shake-flask experiments.
Aero-YieldBorn from academic research at the University of Maryland, Baltimore County’s Center for Advanced Sensor Technology, Aero-Yield makes patented breathable shake flasks for early bioprocess development. Its walls improve oxygen transfer and carbon-dioxide removal while supporting non-invasive sensor integration, addressing the oxygen limitation common in conventional shake flasks. The company’s 500 mL flask is pre-sterilized and designed to deliver more productive cell growth without changing a laboratory’s workflow.ELLICOTT CITY, MD
Applied BioPhysics, IncFounded in 1991 by the inventors of Electric Cell-substrate Impedance Sensing, Applied BioPhysics manufactures ECIS® instruments and electrode arrays that monitor living cells in tissue culture in real time. Based in Troy, New York, the company applies biophysical research to cell research and drug discovery, with 95 percent of its products made at its U.S. facility. Its systems give researchers a label-free way to study cell behavior while maintaining active connections with the academic community that helped shape the technology.TROY, NY
BioSpherix, LLCFor more than 30 years, BioSpherix has been known for putting the needs of living cells at the center of laboratory design. The Parish, New York biotechnology company develops controlled environments for researchers and biomanufacturers, with its work cited in thousands of peer-reviewed publications worldwide.PARISH, NY
PhlotonicsPhlotonics develops light-powered biosensors that measure biological activity for advanced biomanufacturing and drug discovery. Founded around a core technology co-developed by its three PhD co-founders, the Rochester company applies photonics to real-time bioprocess monitoring, with peer-reviewed studies supporting its approach.ROCHESTER, NY