Founded in 1991 by the inventors of Electric Cell-substrate Impedance Sensing, Applied BioPhysics manufactures ECIS® instruments and electrode arrays that monitor living cells in tissue culture in real time. Based in Troy, New York, the company applies biophysical research to cell research and drug discovery, with 95 percent of its products made at its U.S. facility. Its systems give researchers a label-free way to study cell behavior while maintaining active connections with the academic community that helped shape the technology.
BioSpherix, LLCFor more than 30 years, BioSpherix has been known for putting the needs of living cells at the center of laboratory design. The Parish, New York biotechnology company develops controlled environments for researchers and biomanufacturers, with its work cited in thousands of peer-reviewed publications worldwide.PARISH, NY
PhlotonicsPhlotonics develops light-powered biosensors that measure biological activity for advanced biomanufacturing and drug discovery. Founded around a core technology co-developed by its three PhD co-founders, the Rochester company applies photonics to real-time bioprocess monitoring, with peer-reviewed studies supporting its approach.ROCHESTER, NY
Scientific BioprocessingScientific Bioprocessing grew from Fluorometrix Corp., formed in 1999 around optical sensing patents for monitoring conditions inside living cell cultures. Now part of a history that includes Scientific Industries and aquila biolabs, the company helps bioprocess researchers replace guesswork with real-time data, particularly in shake-flask experiments.PITTSBURGH, PA
Microprobes for Life ScienceFounded in 1983 by Martin Bak, Gaithersburg-based Microprobes for Life Science designs and fabricates implantable neural microelectrodes, multichannel arrays, and related systems for electrophysiology research. With more than 30 years of microelectrode expertise, the company is known for tailoring neural interfaces to specialized research applications, including its chronic Floating Microelectrode Array and wireless successor. Microprobes serves research institutions and pharmaceutical and medical-device companies worldwide and is ISO 9001:2015 certified.GAITHERSBURG, MD