Phlotonics develops light-powered biosensors that measure biological activity for advanced biomanufacturing and drug discovery. Founded around a core technology co-developed by its three PhD co-founders, the Rochester company applies photonics to real-time bioprocess monitoring, with peer-reviewed studies supporting its approach.
Applied BioPhysics, IncFounded in 1991 by the inventors of Electric Cell-substrate Impedance Sensing, Applied BioPhysics manufactures ECIS® instruments and electrode arrays that monitor living cells in tissue culture in real time. Based in Troy, New York, the company applies biophysical research to cell research and drug discovery, with 95 percent of its products made at its U.S. facility. Its systems give researchers a label-free way to study cell behavior while maintaining active connections with the academic community that helped shape the technology.TROY, NY
Layer Metrics IncFounded by optics and photonics entrepreneurs Clare Murphy and Dominic Murphy, Layer Metrics Inc. develops optical metrology and sensing systems that monitor and control advanced manufacturing processes in real time. Its proprietary iDaR™ technology uses synchronized multiplexed measurements to help manufacturers reduce yield loss, including in high-value semiconductor and additive manufacturing applications. CTO Dominic Murphy brings more than 25 years of experience commercializing in-line optical monitoring instruments.ROCHESTER, NY
Scientific BioprocessingScientific Bioprocessing grew from Fluorometrix Corp., formed in 1999 around optical sensing patents for monitoring conditions inside living cell cultures. Now part of a history that includes Scientific Industries and aquila biolabs, the company helps bioprocess researchers replace guesswork with real-time data, particularly in shake-flask experiments.PITTSBURGH, PA
Fluid Photonics CorporationNew York-based Fluid Photonics Corporation develops portable optical sensing platforms that give mining and hydrometallurgical operators continuous, real-time chemical data. Its Hummingbird™ system uses a fluid-fluid microreactor and self-contained instrumentation to turn emerging sensing technologies into process-control tools for demanding and remote environments. The privately held company also supports sensor development from laboratory testing through field deployment.LINDENHURST, NY