Founded by physicists Laura Philips and David Grier, Spheryx develops particle-characterization instruments and analytical services built around its patented Total Holographic Characterization® technology. Its xSight system measures suspended particles in complex fluids while distinguishing particles of similar size by composition, giving researchers and manufacturers a closer look at formulations such as biologics and wastewater. The company’s scientific leadership combines holographic microscopy expertise with experience in soft matter, optics and biopharmaceutical applications.
Dispersion Technology, IncFounded in 1996 by Philip Goetz and Andrei Dukhin, Dispersion Technology develops and manufactures instruments that use acoustic and electroacoustic methods to characterize concentrated dispersions, emulsions, and porous materials. From its Bedford Hills laboratory, the company also develops measurement applications and software, with more than 850 instruments installed internationally. DTI’s technical work includes seven U.S. patents, international standards for acoustic particle sizing and zeta-potential measurement, and three editions of an Elsevier scientific book.BEDFORD HILLS, NY
AirPhotonFounded in 2012 by scientists working in particulate measurement since the early 1990s, AirPhoton designs and manufactures field-deployable instruments for measuring airborne particulates and trace gases. The Maryland-based company, now part of GRASP Earth, pairs laboratory-level measurement capability with practical deployment in networks and missions including SPARTAN and NASA’s MAIA. Its instruments are built alongside scientific expertise in interpreting particulate and gas measurements, rather than sold as standalone hardware.BALTIMORE, MD
PolyLC IncFounded in 1985 by the late Dr. Andrew J. Alpert, PolyLC Inc. is known for pioneering HILIC chromatography and helping scientists solve difficult analytical separations. The Columbia, Maryland company develops specialized tools for researchers working with complex biomolecular samples, including a portable HPLC system for hemoglobin analysis.COLUMBIA, MD
The Solubility CompanyBorn from a 2013 University of Helsinki research idea, The Solubility Company became a 2018 university spin-out providing preclinical measurement services to pharmaceutical and biotechnology researchers. Its laboratories in Helsinki and Quakertown use proprietary machine vision to study how materials dissolve, even from very small samples, giving development teams earlier insight into drug formulation and solid form.CAMBRIDGE, MA