For more than 25 years, Vapotherm has made respiratory-support devices built around high velocity therapy, its mask-free approach for spontaneously breathing patients from premature neonates to adults. Based in Exeter, New Hampshire, the medical-device company’s portfolio includes the HVT 2.0 and Precision Flow systems, alongside a portable ventilator developed with Flight Medical. Vapotherm products are used in more than 2,400 hospitals across over 40 countries.
Monaghan Medical CorporationFrom its Plattsburgh, New York base, Monaghan Medical Corporation develops and manufactures respiratory-care devices, including the NasoNeb® powered nasal delivery system that brings clinic-inspired medication delivery into the home. The company’s mechanical-design work is supported by a Global Aerosol and Research Laboratory, and its broader respiratory portfolio includes AeroChamber®, Aerobika®, and AeroEclipse® brands.MEDINA, OH
Inogen, IncSince 2001, Inogen has developed and makes portable oxygen concentrators for people receiving respiratory therapy, with its pulse-dose systems designed for use beyond the home. The company says it has sold or rented more than one million units worldwide and distributes its concentrators through international partners in more than 59 countries. Its current product line includes the Inogen One G5 and the newer Rove systems, supported by published clinical research and a focus on extending device service life.BROOKLYN, OH
ScopemedScopemed is a Brunswick, Ohio medical-device company founded by certified anesthetist Tosan Ugbeye and aerospace engineer Shawn Iravanchy. Drawing on clinical and engineering experience, it develops respiratory-care solutions for hospitals and procedural settings, including its O2rizon™ mask for non-invasive oxygen delivery and airway support.BRUNSWICK, OH
Respair, IncBorn from University of Pittsburgh clinical research, Pittsburgh-based Respair develops airway devices for ventilated patients, beginning with RelianceET, a breathing tube designed to replace the conventional inflatable cuff with soft baffles that seal the airway without added pressure. Founded by physicians Carl Snyderman and Garrett Coyan, the company brings surgeons, engineers, and entrepreneurs together to address ventilator-associated complications. Respair completed hundreds of benchtop tests and received a Phase I SBIR award from the NIH while advancing the device toward regulatory submission.PITTSBURGH, PA