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Founded by Jonathan Cohen, 20/20 BioLabs develops and commercializes AI-powered laboratory blood tests aimed at detecting cancer and chronic disease earlier. Its OneTest for Cancer uses a protein tumor-marker approach and can be collected at home with an upper-arm device, while the company’s longevity test measures inflammation-related biomarkers to support proactive health decisions. The company’s laboratory is CAP accredited and CLIA licensed, and its multi-cancer test has performed in blinded studies conducted by the U.S. National Cancer Institute.
Founded by nephrologist Alfredo Zarate, MD, BioMedical Enterprises develops medical devices aimed at difficult clinical problems, including bloodstream infections, temperature management and cancer screening. Its earlier work on hemodialysis produced a patented needle designed to reduce blood-cell damage and inflammatory-factor release, earning support from the National Institutes of Health’s commercialization program. The company’s newer devices are built around identified unmet needs and are being prepared for validation and commercialization.
Founded in 1992, BIOTECHPHARMA CORP is a Delaware pharmaceutical company built around acquiring and developing medicines for healthcare markets in the Middle East. It works with international partners to bring specialty generic products and rapid diagnostic solutions to healthcare providers, supported by regulatory and distribution services.
Founded by Glen Ceiley in Chicago in 1973, bisco industries has grown from a two-location operation into a broad distribution company serving manufacturers across North America and beyond. It supplies production components for industries such as aerospace and military, with local offices and inventory positioned to support customers close to their operations. bisco also helps customers manage purchasing and inventory through tailored supply-chain programs.
Family-owned since 1866, Bizerba grew from a small German workshop into a global manufacturer known for precision in food-handling equipment. It serves food retailers, producers and logistics operations with weighing and slicing systems supported by software and service.
Family-owned and operated in Hagerstown, Maryland, BJ’s Custom Creations decorates apparel and promotional items, with its embroidery and screen-printing work produced in-house. Founded in 1995, the company is also known for intricate applique-focused textile engraving and its My Home Towne line of handmade wooden building replicas. BJ’s serves customers from its Hagerstown facility with custom work ranging from small digital-print orders to large apparel runs.
Founded by former management consultants Ed Boyce and Sarah O’Herron, Black Ankle Vineyards grows, makes, and bottles wines entirely from grapes cultivated on its Maryland farms. The operation began with its first plantings in 2003 and 2004 and now farms 108 acres of vines across 577 acres, with sustainability built into everything from vineyard work to a tasting room made largely from materials grown or gathered on the property. Visitors can taste the wines and enjoy local fare among the vines in Mount Airy.
Bottled by the Itaberco family in Maryland, Blackbird Specialty Beverage Co. makes concentrated, shelf-stable cocktail syrups for mixologists building frozen or batched craft drinks. Its mixes use premium organic and natural ingredients, while its flavor compounds bring real fruit and juice to beer without the handling demands of a purée. The company’s range includes distinctive bar-ready bases such as Espresso and Bitters, designed to give professional beverage programs a consistent pour.
Richard L. Blackburn Jr., a welding and iron-work veteran with more than 20 years of experience, leads Blackburn Welding & Iron Works Inc. in Huntingtown. The company creates custom steel work for contractors and other clients, carrying projects from an initial idea through fabrication and installation.
Founded by former U.S. Navy SEALs and special operations professionals, Baltimore-based BlackSea Technologies builds unmanned maritime systems and provides the operational support to deploy and sustain them. Its GARC surface vessel is already in production at the former Bethlehem-Fairfield Shipyard, where the company says a completed unit currently leaves the line each day. BlackSea pairs that manufacturing work with mission systems such as Mainstay, its open autonomy architecture, and maritime logistics for contested and austere environments.
Born in an Adelaide backyard shed in 1975, family-owned BlastOne International supplies and engineers blasting and coating systems for industrial contractors, including custom facilities, equipment, abrasives and training. From its Columbus base, the company now supports customers through nearly 400 employees and a distribution network spanning 25 locations on four continents. Its particular strength is combining hands-on surface-preparation know-how with engineered, increasingly robotic blast-and-paint facilities for demanding defense, marine and heavy-manufacturing work.
Since opening a small Baltimore mop-making shop in 1908, Blind Industries & Services of Maryland (BISM) has grown into a nonprofit manufacturer and service organization that creates products for government, military, and private customers while employing blind and low-vision people. BISM also provides independence training and rehabilitation for people of all ages, with manufacturing and training operations spanning four states and the District of Columbia. Its textile operations are registered to ISO 9001:2015, and BISM describes itself as Maryland’s largest employer of blind and low-vision individuals.
Founded in 2009, Blink Charging designs, manufactures, owns and operates electric-vehicle charging equipment and a cloud-based network that manages charging stations and session data. The Bowie-based company has deployed thousands of chargers across the United States and supports installations with site planning, maintenance and 24/7 customer service. Its two manufacturing facilities hold ISO 9001:2015 quality-management certification.
BLOCKsynop develops the Neural Blockade Monitor, a noninvasive device designed to give anesthesiologists objective, real-time measurements of regional nerve-block effectiveness. Established after CTO Wayne Sternberger received the inaugural Johns Hopkins University Applied Physics Laboratory Archimedes Award in 2020, the company grew from collaboration between systems engineering and pediatric anesthesiology. Its second-generation prototype has been validated in studies involving adult and pediatric anesthesia, while remaining investigational and not approved for sale in the United States.
BLT World supplies conveyor-belt skirting and dust-control systems tailored for American bulk-material-handling operations. Its distinctive approach centers on non-contact sealing, including the patented German-designed AirScrape system, which helps contain dust while avoiding belt friction and damage. The company serves industrial settings across North America, from mining and ports to agriculture and recycling.
Blue Badger makes rugged, practical ID badge holders designed to keep workplace badges and access tokens organized and comfortable to wear. Its BlueBadger+ system adds below-badge access-tab mounting and modular TabHangers, while the company’s products are proudly made in the U.S.A. Blue Badger is a veteran-owned small business.
Blue Origin is a human spaceflight company pursuing a multigenerational vision of people living and working in space for the benefit of Earth. Its work centers on lowering the cost of access to space through reusable vehicles, including New Glenn, while developing systems for lunar exploration and future space infrastructure.
Engineering NIR solutions since 1996, Blue Sun Scientific is a Maryland manufacturer known for keeping its instruments in service long after they are built. The company makes Phoenix analyzers for food and agriculture customers who need quick, non-destructive composition data, and supports them with a technical team averaging more than 10 years of hands-on NIR experience.
Blue Thunder Promotions is a regional promotional-products company serving organizations across Washington, D.C., Maryland, and Virginia. It develops branded items and campaign ideas for clients ranging from universities and financial institutions to hospitals and community events, with a particular emphasis on useful giveaways and curated promotional themes.
Founded by physicist Dr. R.D. Vispute, Blue Wave Semiconductors is a Baltimore-based research company known for developing thin-film technology for universities, government programs, and industrial laboratories worldwide. Its work combines deposition equipment with specialized development services for customers exploring advanced materials and electronic or photonic devices.