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From its Rockville base, Advanced BioScience Laboratories (ABL) develops and manufactures viral products for vaccines, gene therapies, oncolytic therapies and immunotherapies as a contract development and manufacturing organization. ABL brings more than 60 years of experience working with industry, government and academic partners, including over 30 years focused on viral-vector development and GMP production. Its Rockville facility is ISO 9001 accredited for viral drug-substance and aseptically prepared drug-product manufacturing, and the company has translated more than 100 processes from the laboratory bench into GMP suites.
For more than 45 years, Advanced Blasting Technology, Inc. has developed patented, non-explosive blasting devices for mining and quarrying operations worldwide. Its RockLock stemming plugs improve borehole confinement and fragmentation, while the SUREfire shock-tube starter provides dependable initiation without explosive primers. Based in Watertown, New York, the company brings an explosives-industry perspective to product development focused on safer, more reliable blasts.
Advanced Branding Solutions produces custom vehicle wraps and graphics, screen-printed and embroidered apparel, commercial printed goods, signs, event displays, promotional items, trophies and awards. Its stated capabilities include in-house design, printing, fabrication, embroidery, manufacturing, and installation, serving contractors, trades, schools, teams, retailers, professional services, and other businesses in Maryland, Washington, D.C., Virginia, and nationwide.
Since 1999, Advanced Carbide Grinding has grown from a garage-sized shop founded by five skilled professionals into a 100,000-square-foot, three-shift operation in Derry, Pennsylvania. Today, co-owners David Butz and Jim Elliott remain hands-on as the company produces precision-ground components for manufacturers across western Pennsylvania and beyond. Its ISO 9001:2015-certified quality system reflects a culture built around getting demanding work right the first time.
Founded in 1992 as a captive purification facility for a local graphite machine shop, Advanced Carbon Technologies now provides high-temperature purification and produces pyrolytic graphite for demanding industrial applications. Its Topton, Pennsylvania operation has more than 25,000 square feet of manufacturing space and 11 vacuum induction furnaces, supporting projects from exploratory testing through production with rapid turnaround. ACT is part of the GMI Family of Companies, which also provides related graphite machining capabilities.
Incorporated in 2006, Advanced Chemical Concepts, Inc. supplies and custom-designs chemical solutions, including high-performance additives for metalworking and industrial lubricants. The company pairs technical assistance and field work with supply-chain support, serving customers from strategic stocking locations throughout the upper Midwest. Its team brings more than 100 years of combined experience in producing, selling and managing chemicals and chemical companies.
Founded in 2001 by two longtime metalworking-lubricant professionals, Advanced Chemical Solutions makes metalworking fluids and develops tailored formulas for demanding machining applications. The Orrville-based company distinguishes itself from larger brands by pairing more than 60 years of its founders’ field experience with application-specific blends and practical fluid-management support, including for exotic materials and both large central systems and small shops.
Since 1967, Advanced Chemicals Inc. has provided custom chemical processing and manufactured metalworking lubricants, with capabilities spanning powder processing from laboratory work through large production runs. The Philadelphia company also makes lubricants for the drawing-and-ironing beverage and food can industry, while supporting customers with custom blending and toll processing.
Founded in 1983 by racer Kerry Hitt, Harrisburg’s Advanced Composite Products fabricates custom composite parts entirely in-house, from design and prototyping through production. Its 35,000-square-foot facility serves demanding projects ranging from race-car bodywork to aircraft and government components, including parts for Johns Hopkins Applied Physics Laboratory’s Dragonfly drone destined for Titan. ACP’s racing roots remain visible in its wind-tunnel-tested race bodies and parts, shaped by Hitt’s experience as a driver and composite manufacturer.
Advanced Composites grew from two automotive compounders founded in Ohio and Tennessee in the mid-1980s, joining under Mitsui Chemicals in 2003. Nearly four decades later, the company develops thermoplastic materials for North American automakers and their suppliers, with its work recognized by a 2024 SPE Automotive Innovation Award for Rivian exterior cladding.
Advanced Concrete Systems, Inc. has manufactured Superior Walls precast foundation systems since 1986 and says it has produced more than 40,000 foundations. The Middleburg, Pennsylvania company makes custom-designed, insulated concrete foundation panels in a factory-controlled environment and installs them at building sites. It is an independently owned licensee of Superior Walls of America, Ltd.
Founded in 2016, Advanced Construction Robotics, Inc. develops and builds robotic equipment for construction, with a focus on automating rebar installation. Its field-deployed TyBOT and IronBOT robots perform rebar tying and placement work on infrastructure projects, while ACR also provides related deployment and support services.
From its Waterford, NY facility, Advanced Controls & Automation makes precision-machined components, applies tungsten-carbide HVAF coatings, and designs automated manufacturing cells. The company emphasizes American-made production, employing local talent and supporting domestic supply chains while serving customers across Upstate New York and the Capital District. Its online quoting system accepts STEP files and provides material traceability, with a stated 24-hour quote turnaround.
Employee-owned since 2021, Advanced Conversion Technology is a small Pennsylvania manufacturer that has served the U.S. military since 1981. ACT is known for keeping engineering, manufacturing, and testing together under one roof, where its team develops rugged power solutions for demanding defense applications. Its quality system is certified to AS9100D and ISO 9001:2015.
Founded in 2003 as an R&D company, Advanced Cooling Technologies, Inc. designs and manufactures thermal management products, specializing in custom applications of two-phase heat transfer technology. Its products are used in spacecraft, military vehicles, medical equipment, and HVAC systems, and its operations span thermal engineering and production facilities in Pennsylvania and California.
Advanced Couplings manufactures industrial couplings and sealing components, including gaskets, for demanding fluid-handling applications. Its product-focused operation is supported by locations serving customers across multiple markets, with gaskets given particular attention as a core specialty.
Advanced Cryogenic Enterprises has spent nearly 20 years reducing rubber, specialty plastics, and other materials to precise particle sizes through ambient and liquid-nitrogen-assisted grinding. Employee-owned and operated, ACE has grown from a 3,000-square-foot pilot plant opened in 2008 to two locations totaling 75,000 square feet. The Akron company works from small laboratory trials through multiple truckloads per week and also makes ACE-CAL moisture-control products for rubber manufacturing.
Advanced Dental Lab, Inc. manufactures dental prosthetics, combining hands-on laboratory experience with newer digital tools such as the 3Shape Unite platform. Based in Lebanon, Pennsylvania, the lab emphasizes dependable service and offers free local delivery to its customers.
Established in 2001, Advanced Design Solutions Inc. designs and manufactures material-handling packaging, with a primary focus on steel racking and assemblies. It serves the automotive industry and operates manufacturing facilities in Stratford, Ontario; Middletown, Ohio; and Lawrenceburg, Tennessee. The company also provides in-house design and prototyping to develop customer-specific concepts for production.
Kent natives run Advanced Display as a 100% custom digital printing house, creating signs, banners and graphics for local businesses and community projects. The locally owned shop has served the area for more than 35 years, with custom vehicle lettering and wraps among its distinctive work.