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Founded in 2021 to commercialize healthcare technologies developed at The Ohio State University, HDO Health is a Columbus-based medical-device company built around a service-minded, data-driven approach. Its founding team brings nearly a century of combined experience, including military, trauma surgery and biomedical-engineering backgrounds, to address difficult needs faced by emergency and combat-care providers. The company’s lead product is the Journiquet™, a junctional tourniquet designed with input from more than 300 end users.
Founded in Solon, Ohio, in 1937, HDT Global is a manufacturer known for supporting military and expeditionary operations with equipment engineered for demanding field conditions. The company also serves industrial and medical customers through in-house engineering, manufacturing, and product support, with ISO 9001:2015 certification across its facilities.
Founded in Solon, Ohio, in 1937, HDT Global is a manufacturer and systems integrator known for supporting U.S. and allied military customers in austere environments. The company develops mission-ready equipment and provides engineering and manufacturing services for defense, government, industrial, and commercial users. Its facilities across the United States and Europe are certified to ISO 9001:2015.
HDX Reman is a Pennsauken, New Jersey specialist focused on keeping heavy-duty truck fleets moving through remanufactured drivetrain components. The company supplies exchange-ready units to commercial partners such as OEMs and wholesale distributors, using technical knowledge and strict quality processes to support consistent performance.
Veteran- and minority-owned HDZ Fab n Design, LLC. operates a full-service steel fabrication and welding shop in Wampum, Pennsylvania, specializing in structural steel work and custom fabrication. Its team includes steel erectors, offers CAD capabilities, and supplies and installs building materials such as bar joists and roof decking. All of the company’s welders hold AWS D1.1 certifications.
Heacock Lumber is a family sawmill dating to 1918 that produces rough-cut hardwood lumber and custom-saws logs at its Bucks County mill. The Hunsberger family has operated the sawmill since purchasing it in 1974, continuing a local tradition that includes making survey stakes and turning milling byproducts into mulch and firewood. Its timber work follows Sustainable Forestry Initiative of Pennsylvania practices, with an emphasis on long-term woodlot management rather than clearcutting.
Founded in 1992, Head Nutrition Group is the North American operation of Shandong Head Group, manufacturing plant-based HPMC capsules and cellulose ethers for health, nutrition, pharmaceutical and food applications. The company describes itself as the first and only vertically integrated producer of HPMC capsules, with more than 30 years of manufacturing experience, production capacity reaching customers in over 60 countries, and eight North American warehouses supporting capsule supply. Its GMP-operated facilities produce NSF-certified capsules that are also Kosher and Halal certified.
Headley Inn Winery & Vineyard operates an on-premise winery producing handcrafted Ohio wines from hand-picked grapes, including red and white wines with dry, semi-sweet, and sweet profiles. It also operates a historic bed and breakfast, tasting room, and venue for private events.
HeadStrait Labs, founded by biomedical engineers Alyssa Theroux and Mary Squire after meeting in class, develops patient-centered emergency-transport devices for head and neck stabilization. Its EVAC-1 combines an adjustable splint with SMARTmotion sensors that track movement and provide real-time feedback, giving care teams information to support safer transport and post-event review. The Pittsburgh startup has received $225,000 in local backing since 2023 and was named a 2025 UpPrize semifinalist.
Headstrong Mouthguards provides custom fit, high quality mouthguards for adolescent and adult athletes by taking molded impressions of each customer's mouth to produce superior guards compared to standard boil-and-bite mouthguards.
From its Ithaca, New York engineering offices and factory, Headwaters Solutions designs and fabricates hydrogen and synthesis-gas plant equipment for heavy industry and clean-energy projects. The privately held firm focuses on smaller-scale hydrogen systems, including steam reformers and PSA purification plants, while also revamping legacy facilities and supplying high-pressure refueling equipment. Its senior team brings more than 100 years of combined experience, and company principals hold more than 40 issued U.S. patents related to hydrogen and syngas applications.
Founded in 2020 by Dr. Biju Jacob and Neeraj Kumar, Healium Intelliscan develops AI-integrated ultrasound technology for early detection and management of chronic kidney disease. Its system combines renal ultrasound imaging with digital biomarkers and predictive analysis, including patient-specific perfusion modeling to help identify CKD and its possible causes. The company submitted its device for FDA 510(k) clearance in 2024; clearance is pending.
Born from co-founder Sharon Samjitsingh’s experience with severe asthma, Rochester-based Health Care Originals develops cardiopulmonary wearable systems and the software that turns respiratory data into usable insight. Its ADAMM platform supports asthma and COPD care, telemedicine, and clinical research by tracking symptoms such as cough and breathing patterns between visits as well as during remote consultations. The company’s technology has received recognition including CES 2015 honors and Innovation World Cup awards.
Founded in 2005, family-owned Health Care Products, Inc. manufactures feminine hygiene and adult incontinence products in Coldwater, Ohio. The company supplies U.S.-made goods to private-label, institutional, and dollar-market customers, and also distributes tampons.
Since 1963, three generations of the Gruber family have built Health Extension around making pet food for dogs and cats, including small-batch, US-made recipes. Based in Hauppauge, New York, the company is especially distinctive for its gently cooked dog food, prepared in bone broth and sold in shelf-stable, ready-to-serve pouches rather than requiring freezing or thawing. Its recipes use more than 30 superfoods and undergo over 140 quality checkpoints, with veterinarian-formulated options designed to provide complete and balanced nutrition.
From Long Island’s north shore, Health Star Dental operates a full-service dental laboratory serving dentists across the United States. The lab combines conventional casework with digital submissions through its own web portal and major scanner platforms, while producing crowns, removable prostheses, and orthopedic appliances. Health Star also documents the USA FDA-approved and European CE-marked materials used in each case.
Healthcare Lighting is a specialized Acuity Brands Lighting brand founded around a singular mission: improving patient outcomes through better-designed hospital environments. It develops lighting systems for healthcare settings that help patients feel more comfortable while giving caregivers clearer control over their workspaces, including solutions compatible with nLight and nLight AIR.
For more than 20 years, Healthcare Technology Corporation has been known for practical, pre-engineered support solutions developed in close collaboration with healthcare planners, architects and contractors. The Fairport, New York company manufactures Accu-Mount™ systems for facilities that need overhead medical equipment supported through new construction, renovation or future upgrades.
Founded in 2015 by Dr. Ramanan Laxminarayan, HealthCubed India develops portable point-of-care diagnostic systems that screen for more than 55 health parameters. Its HealthCube XL and SE devices are designed for rapid testing in clinics, health camps and remote areas, operating with minimal training and without electricity or internet. The company says more than one million beneficiaries have been registered in its ecosystem and 2.5 million tests have been performed across four continents.
Founded in 1978 as Zoster, HealthTech Bio Actives (HTBA) develops and manufactures naturally sourced citrus flavonoids and vitamin B12 active forms for pharmaceutical, nutrition, food and animal-health applications. Its Beniel, Spain, facilities include a state-of-the-art vitamin B12 plant, while applications labs in Barcelona and Cincinnati support customers across more than 60 countries. HTBA is particularly distinctive for patented solvent-free flavonoid production and its upcycled citrus-based sweetener, Citrose.