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Little Creature, LLC is a small, human-focused game studio established in 2023 that creates tabletop and video games. Its physical products include the Tournament Arc card game, game expansions, collectible cards, stickers, enamel pins, medals, and card storage tins.
Founded in 1993 by Ava DeMarco and Rob Brandegee, Little Earth Productions makes licensed fashion accessories and apparel for professional and college sports teams. The Pittsburgh-based company grew from a home business producing accessories from recycled materials and is known for manufacturing the Pittsburgh Steelers’ Terrible Towel.
Chef and author Cara Mangini founded Little Eater around a simple idea: vegetables belong at the center of the American plate. Based in Columbus, the company works with Ohio farm partners to create seasonal food for home meals and gatherings, while Mangini’s award-winning cookbook carries the same produce-first approach to cooks beyond the kitchen.
Built from an abandoned mechanic’s shop in Athens, Little Fish Brewing Co. has brewed farmhouse, barrel-aged, and mixed-culture beers since co-owners Jimmy Stockwell and Sean White opened it in 2015. The independently owned brewery became a farm-to-table restaurant in 2017 and now operates taprooms in Athens and Dayton, pairing its rotating beers with locally sourced food. Little Fish is especially known for its Ohio-grown brewing program, including the state’s first commercial 100% Ohio-grown beer since at least Prohibition, and its award-winning barrel-aged sours.
Born from Karen Moffitt’s habit of baking homemade treats for her children and sending them to college friends, Little Miss Moffitt makes artisan cookies and dessert bars designed to carry a personal message. Its signature “Hugs Disguised as Cookies” package places a chosen cookie in a cookie-sized container with a customizable label, turning a baked treat into a small act of kindness. Based in Norristown, the bakery also handles corporate gifting with shipments to multiple recipients and personalized notes.
Little Mountain Precision, LLC is a defense and commercial machining manufacturer offering turnkey machining and sub-assembly services. Its capabilities include precision CNC machining and design-for-manufacture support, and the company makes firearm components and assemblies.
Little One Nutrition Co. is developing goat-milk infant nutrition designed to support babies from day one. The forthcoming company pairs its baby-feeding product with Momshift, a community offering mothers honest conversations, expert guidance, and peer support through the changes of motherhood.
Founded by former actor Arnold Wilkerson in 1985, Little Pie Company bakes handmade American pies and other desserts fresh in Manhattan’s theater district. Its “theater of baking” puts bakers behind picture windows, where locally sourced ingredients become hand-pinched, small-batch pies such as its Sour Cream Apple Walnut and Mississippi Mud varieties. The company also ships its desserts fresh nationwide and supplies wholesale customers.
Since 2009, Medina’s locally owned Little Red Quilt House has been a welcoming quilting shop offering traditional fabrics, patterns, kits and supplies, along with long-arm finishing and instruction. The shop stands out as a gathering place for quilters of every skill level and turns donated materials into about five quilts each month for charitable organizations through its Benevolence projects. It also transforms meaningful clothing, from school T-shirts to keepsake garments, into memory quilts.
Little Round Industries is a family-run precision sheet metal fabrication shop located in Hatfield, PA, specializing in high-quality metal fabrication for diverse industrial needs. Founded by Dick Burk in 1991, the company operates a 42,000 sq ft facility with modern equipment including TRUMPF lasers and press brakes.
Little Tikes makes children’s toys built around active and imaginative play, from its recognizable Cozy Coupe ride-on to backyard play equipment and pretend-play furnishings. Based in Hudson, Ohio, the company also manufactures some products in the United States and supports owners with replacement parts for many of its toys. Little Tikes is part of MGA Entertainment, Inc.
Little Trees makes air fresheners, a product Julius Sämann invented in 1952 after a milk truck driver complained about the smell of spilled milk. The company says its Tree air fresheners are made at factories in Watertown, New York, and DeWitt, Iowa, and has expanded its range with additional air-freshening formats.
Created in 2015 by Dr. Kathleen McCue, a family nurse practitioner and International Board Certified Lactation Consultant, LittleBeam Nursing Pillows makes ergonomically shaped, memory-foam supports for breastfeeding and bottle-feeding. The semicircular pillows are designed and made in the USA, with a machine-washable cotton cover and a compact form suited to travel, while also serving for supervised tummy time and propping. LittleBeam grew from McCue’s Metropolitan Breastfeeding practice and was created by a mother with lactation expertise for parents and babies.
Born as Gabe’s undergraduate-thesis distraction in 2012, Littlecat Labs is a Brooklyn-based audio design project that develops compact high-fidelity speakers. Its signature Sphere speaker uses a 3D-printed triple-helix bass-reflex port, an unusual acoustic design refined through years of prototypes from a bedroom workshop to the Brooklyn Navy Yard. The project’s development is currently on hiatus.
Chartered in 1916, Littlestown Foundry is a Pennsylvania aluminum sand-casting foundry that now produces more than 95% of its business in commercial aluminum castings. The company has grown from a 16-person gray-iron operation into a 70-employee facility with in-house machining and testing, serving customers across sectors including electrical, firefighting and aerospace. Its quality management system has been ISO 9001 certified since 2003.
LittleStuff4u Cosmetics is a small woman-owned business led by Sandra that makes organic makeup and natural skincare in the USA. Built around more than two decades of helping customers find products for their individual needs, the company emphasizes botanical ingredients, sensitive-skin-friendly formulas, and personal service rather than mass-market beauty. It also offers samples and unlabeled bulk makeup for buyers who want to try or purchase its formulas in larger quantities.
Philadelphia-area biotech LIV Process develops a patented visualization system that makes otherwise invisible Clostridioides difficile spores visible on healthcare surfaces in real time. Its water-based solution binds to proteins on the spores and fluoresces under a dedicated light, helping hospital environmental-services teams target cleaning and verify that contamination has been removed. Founded by inventor and longtime medical-product executive Michael McIntyre, the company operates from headquarters in Ardmore with research and development in Cambridge.
Established in 2019 by architects, modular-housing experts, and a physician, Liv-Connected brings architectural and health expertise to factory-built housing. The company is best known for supplying FEMA’s temporary housing response for Lahaina wildfire survivors, delivering 109 homes in less than four months. Its work focuses on making thoughtfully designed modular homes more attainable for people facing housing and disaster-recovery needs.
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LivaNova PLC is a global medical technology company that develops and manufactures medical devices and therapies. Built on decades of experience, it has more than 3,000 team members and a 50-year legacy in cardiopulmonary perfusion, while its VNS Therapy has been used for more than 30 years.
Founded in New York in 1987, Livaura develops skincare, lip care and beauty tools through a portfolio of beauty brands. Its best-known signature is pH-activated lip color that adapts to the wearer, alongside its long-running retinol skincare line. Livaura says its products are made in the United States and Korea, have reached more than 50 countries, and have surpassed 100 million units sold.