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MD
Four generations after Leonardo Alarcon began working with coffee beans in southwest Venezuela, Orinoco Coffee & Tea remains a family-rooted roasting company with its home in Maryland. Its work carries a 1909 heritage into custom-roasted coffee and premium tea for retailers, coffee shops, and grocery chains across the United States.
With nearly a century of flare-making behind it, Orion Safety Products manufactures emergency flares and signaling devices for roads, waterways, homes, and the outdoors. Its products are engineered and made in the USA at facilities in Indiana and Pennsylvania, while corporate headquarters are in Easton, Maryland. Orion is particularly rooted in marine distress signaling, producing USCG-approved visual distress signals and SOLAS-approved products, and its highway and railway flares are made to UL 912 specifications.
Family-owned and operated since 1992, Orlando Products Inc. has built its Baltimore operation around solving demanding packaging challenges for customers in fields such as aerospace, military, and medical equipment. Its 150,000-plus-square-foot facility houses an in-house engineering team with more than 60 years of combined industry experience, supporting custom packaging work from design through production. The company also runs a recycling program that reuses foam scrap and incorporates recycled material where possible.
As a veteran-owned small business with more than 20 years serving the Washington, DC, and Baltimore metro areas, Orthocare Solutions is known for individualized patient care across four locations. Its clinicians create customized orthotics for patients of all ages and also support hospitals and government healthcare programs with on-site fitting services. The company is certified as a Veteran-Owned Small Business and Minority Business Enterprise, with BOC and ABCOP-accredited practitioners and facilities.
Founded in 2011 through a collaboration between Uppsala University and Karolinska University, OssDsign AB develops and supplies orthobiologics that support bone healing. The Uppsala company now focuses solely on OssDsign Catalyst®, a nanosynthetic, silicate-substituted bone graft substitute designed for spinal fusion and other bone-healing applications. OssDsign became a pure-play orthobiologics company in 2024 after discontinuing its cranial implant business.
Otomagnetics is developing a magnetic injection drug-delivery platform that uses a proprietary magnetic device and biodegradable particles to move therapies non-invasively into hard-to-reach ear and eye tissues. Founded by hearing and neuroscience researcher Didier Depireux, the Gaithersburg company has demonstrated delivery to inner- and middle-ear compartments in animal models, including middle-ear delivery without puncturing the eardrum. Its multidisciplinary team includes CEO Abhita Batra and Chief Medical Officer Karen Stierman, an otolaryngologist with an electrical-engineering background.
Since 1881, Otterbein’s Cookies has baked thin, crispy cookies in Maryland, preserving the signature crunch that began with the Otterbein family’s original recipe. The company still uses that same style of bake and, for its sugar cookies, a deliberately simple six-ingredient formula that has made Otterbein’s a Baltimore-area staple for generations.
Since 1881, Otterbein’s Cookies has baked Maryland’s signature thin-and-crispy cookies, using the same original recipe and method that made the brand a regional staple. The family’s six-ingredient sugar cookie and unmistakable paper-thin crunch remain central to a Maryland tradition now more than 140 years old.
Oversea Distillery brings traditional Chinese baijiu together with American whiskey-making in a Columbia, Maryland, distillery and bar. Its signature distinction is a light-aroma baijiu crafted and aged on U.S. soil, alongside a baijiu aged in China and finished for another year in the distillery’s used whiskey barrels. The venue pairs house-distilled spirits with globally influenced cocktails, food, live entertainment, and flexible event space.
Established in 1999, Owl Cyber Defense Solutions is a Columbia, Maryland cybersecurity company known for pioneering commercial data diode technology and building it in the United States. Its security systems help government and critical-infrastructure organizations move sensitive information across network boundaries, and the company reports deployments in more than 90% of U.S. nuclear power plants.
Founded in 1974, P.F. Industries Inc. in Saint-Martin, Quebec, turns locally sourced spruce and fir into fence components, bed-frame parts and precision-cut lumber for manufacturers. Its 40 years of experience include assembling fence panels and developing specialized wood components, while its employee survey reflects a workplace built around training, advancement and work-life balance.
Family-owned and operated since 1952, P.T. O’Malley Lumber Company manufactures wood products and supplies wholesale lumber from facilities in Pennsylvania, Maryland, and Virginia, with sawmills in Virginia. It has built its business around pallet production and wholesale lumber, and uses sawmill byproducts to make hardwood pellets.
Founded in 1993 as a small research-and-development company, Hagerstown’s P&D Creative Co., Inc. formulates and manufactures non-toxic, biodegradable cleaning products for industrial, institutional and household use. Its Magic 555, MotorPro and Effective brands grew from an early colloidal-chemistry stain remover into a broader cleaning line, while the company also develops custom formulations and private-label products. P&D Creative is an SBA-certified 8(a) small manufacturing and services company and a two-time GSA Multiple Award Schedule contractor serving government customers.
PA Building Supply is a Pennsylvania building-materials supplier formed through the strategic alignment of Myers Building Product Specialists, Shelly’s Building Supply, and Musselman Lumber, all US LBM sister companies. It also operates a Telford component-manufacturing facility producing custom trusses and wall panels, as well as a custom interior and exterior millwork shop.
Founded in 2022 by Michael Pace, Pacesetter Signs and Graphics is an Elkton, Maryland company shaped by its owner’s background in graphic design and more than 15 years in corporate product and project management. Pace built the business around working directly with local entrepreneurs and helping them turn their brand into clear, custom signage, with projects carried from design through installation.
Formed by packaging enthusiasts and innovative designers, Pack Arena is a custom packaging company built around helping brands turn product concepts into practical, polished packages. It supports businesses with design guidance and flexible order quantities, producing packaging for retail and e-commerce products.
Pack Arrow is a custom packaging company that manufactures printed boxes, cartons, mailers, rigid packaging, food packaging, cosmetic packaging, and custom bags. Its capabilities include custom structural design, printing, finishing, inserts, sampling, and bulk production using paperboard, cardboard, kraft stock, corrugated board, rigid board, and specialty stocks.
Founded as a small family operation in 1976, Packaging Services Industries now designs and manufactures custom corrugated packaging and protective foam solutions from three facilities serving the Eastern U.S. PSI is unusual in bringing corrugated box design and foam engineering under one roof, allowing its team to develop integrated packaging systems for more than 2,000 customers. With approximately 400 employees and a 282,000-square-foot headquarters in Williamsport, Maryland, the company combines substantial production capacity with a hands-on design and engineering approach.
Founded in 1990, Packaging Strategies Incorporated designs and manufactures reusable shipping and carrying cases for high-value equipment, with its Baltimore facility handling custom work from prototype through production. Its cases have served every branch of the U.S. Armed Forces as well as aerospace, medical, and advanced-technology customers, and the company also provides systems integration and fulfillment support. PSI is ISO 9001:2015 certified and manufactures in the United States, with more than 4,000 packaging products in its portfolio.
For more than two decades, Padova Technologies has designed, built, integrated, and tested custom IT systems for federal and Department of Defense customers. The Baltimore-area woman-owned small business specializes in mission-driven engineering, from tailored commercial off-the-shelf solutions to high-performance computing and enterprise systems, and operates a manufacturing and integration facility. Padova is HUBZone-certified and maintains an ISO 9001:2015 registered quality management system.