Based in Cincinnati, Intracellular Imaging makes fluorescence imaging and photometry systems for researchers measuring intracellular calcium and other cellular signals. Its InCyt systems combine microscope-based imaging with photometry options, and the company is known for equipment that researchers can learn quickly alongside responsive service and support. Intracellular Imaging also develops application guidance to help laboratories choose between spatially resolved imaging and faster, more sensitive photometry.
Omnitech Electronics, IncFrom Columbus, Omnitech Electronics makes research equipment for behavioral and physiological studies, pairing standard laboratory systems with custom hardware and software for unusual projects. Its instruments help researchers measure animal activity and behavior, while the company also provides hands-on support with installation, software tutorials, and technical questions. Omnitech says its equipment is used by pharmaceutical companies, research institutions, and universities.COLUMBUS, OH
BioInVision IncFounded by biomedical imaging expert David Wilson, PhD, BioInVision is a Cleveland company built around technology developed with Case Western Reserve University. Its CryoViz™ platform helps biotechnology and pre-clinical researchers examine whole mice or organs in three dimensions at microscopic resolution, while the company also applies its imaging expertise to clinical cardiac software.CLEVELAND, OH
Akrotome ImagingIncorporated in Delaware in late 2008, Cleveland-based Akrotome Imaging develops fluorescent molecular probes that help surgeons see cancer and its margins during resection. Its patented FIRE platform uses quenched probes that activate when they encounter tumor-associated enzymes, with the flexibility to be applied in the operating room and used alongside a near-infrared imaging system. The company’s current team has been in place since 2012 and is translating the technology toward breast and non-melanoma skin cancer applications.CLEVELAND, OH
Applied BioPhysics, IncFounded in 1991 by the inventors of Electric Cell-substrate Impedance Sensing, Applied BioPhysics manufactures ECIS® instruments and electrode arrays that monitor living cells in tissue culture in real time. Based in Troy, New York, the company applies biophysical research to cell research and drug discovery, with 95 percent of its products made at its U.S. facility. Its systems give researchers a label-free way to study cell behavior while maintaining active connections with the academic community that helped shape the technology.TROY, NY