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Applied Technology Manufacturing Corporation (ATMC) manufactures precision components and assemblies in Owego, New York. Founded in 1927 as Moore & Steele Corporation, it began by producing railroad track appliances and has since expanded its manufacturing capabilities; its current operations occupy a 20,000-square-foot facility.
Applied Technology Systems, Inc. has been in business since 1994 and supplies a wide variety of CO2 based gas supply systems for treating concrete washout, stormwater, potable, and wastewater applications for the purpose of reducing the pH.
Founded in 1965, Applied Test Systems designs, engineers, and manufactures materials-testing and process-heating equipment at its Butler, Pennsylvania facility. The company grew from Applied Devices, established by manufacturing engineer Norman L. Carroll, and is known for developing custom equipment for testing requirements that standard products may not meet. Its products serve customers worldwide, with on-site calibration accredited to ISO/IEC 17025.
From its New York City creative studio, Apply Stickers designs and makes premium stickers in the USA. The company turns licensed artwork from artists around the world into small, collectible works, using techniques such as screen printing and holographic finishes. Since 2021, Apply has paid more than $465,000 in artist royalties and donated over $50,000 from sticker proceeds to arts and culture organizations.
Appolus, a brand of Goldmine Natural Beauty, develops at-home beauty devices designed to bring dermatologist-style treatments into everyday routines. Founded by former Manhattan corporate professionals who used diamond microdermabrasion themselves, the company focuses on home-use microdermabrasion technology and checks products at approved factories through an independent inspection company.
Established in 1973, APR Tool LLC and Askar Metal Stamping make custom tooling, dies and precision-machined assemblies for manufacturers. The Cleveland operation combines a full-service tool room with metal-stamping capacity, handling projects from small tooling to assemblies weighing up to 6,000 pounds and measuring 48 inches.
Founded in 2003, Mason-based Aprecia Pharmaceuticals develops and manufactures medicines using three-dimensional printing, an approach that enables novel oral drug-delivery forms. Aprecia is the first company to secure regulatory approval and commercialize a 3D-printed pharmaceutical product, Spiritam®, which is produced at its cGMP manufacturing facility. The privately held company combines formulation and manufacturing expertise with a portfolio of 126 granted patents and 52 pending patents.
Aprikus is a Turkey-based botanical ingredients company whose management team brings more than 18 years of experience serving global and regional manufacturers. The company maintains close relationships with local growers and collectors, including its own certified rose and oregano cultivation, while its Turkish production facility is BRC-certified for food applications.
Family-owned and operated in Manhattan since 1914, April Printing Company has grown from a small typesetting operation into a full-service print shop producing everything from everyday business materials to large-format graphics. Now in its fourth generation, the company combines traditional craftsmanship with digital and offset production, direct mail, and custom print solutions. Many employees have been with April Printing for decades, helping sustain the personal service and long client relationships that define the business.
Founded in 1994, APS has spent three decades building a global thermal-printing business around in-house engineering and a manufacturing plant in Botevgrad, Bulgaria, opened in 2004. The company is known for developing compact, application-specific printing technology, including patented easy-loading mechanisms, for customers in fields such as healthcare and automotive. APS operates internationally and maintains certified quality and environmental management systems.
APS Exchange is a digital-asset trading platform offering cryptocurrency purchases, spot trading and derivatives alongside markets for forex, precious metals and energy. Its platform emphasizes AI-assisted service, card-based crypto purchases and a technical architecture designed for a more secure trading environment.
Founded in Dayton in 1975 by materials engineers, APS Materials, Inc. develops and applies plasma-spray metal and ceramic coatings that protect critical components and extend their service life. Still family-owned and operated, the company combines coating research and development with machining and molding support across aerospace, biomedical, semiconductor and infrastructure applications. Its 50,000-square-foot Dayton headquarters includes automated spray systems, cleanrooms and an A2LA-accredited metallurgical laboratory, while its CerAnode division has manufactured U.S.-made cathodic-protection systems since 1984.
Founded in 2017, Montreal-based Apsis Science and Technology develops space-grade radio communication technology and provides engineering support for aerospace and defense programs. Its engineers work alongside client teams on RF and spacecraft systems, embedded electronics, and tailored subsystems, helping turn an early mission concept or a difficult technical problem into a practical design.
Established in 1989 on Long Island, Apsis USA makes and supplies custom automotive accessories, with a particular focus on Corvette interiors and exteriors. The Huntington Station company is also known for real carbon and wood trim work, including restoration pieces for Mercedes and custom parts made from customer-supplied cores. After more than 35 years, Corvette remains its central specialty, spanning models from the C2 through the C8.
Founded by engineers who had grown frustrated with outsourced parts, Cincinnati-based APSX LLC builds compact, made-in-the-USA production equipment for bringing molding and precision machining in-house. Its APSX-PIM desktop injection molding machine, APSX-LSR silicone press and APSX-NANO Swiss CNC lathe are designed for prototyping, short runs and production without the footprint or capital demands of conventional industrial equipment. More than 1,000 machine owners have used APSX equipment since 2017.
Since 1996, APT Manufacturing Solutions has grown from a 2,500-square-foot machining and machine-building shop into a 100,000-square-foot manufacturer in Hicksville, Ohio. The company is known for keeping complex automation work in-house, supporting manufacturers with integrated robotic packaging and welding systems while also developing hands-on industrial education equipment. APT’s operations are ISO 9001 certified, and it is an authorized FANUC system integrator and A3 Certified Robot Integrator.
Headquartered in Syracuse, AptaMatrix is a privately held biotechnology company developing next-generation sequencing-based methods to accelerate the discovery of aptamers—DNA or RNA molecules that can support diagnostic and biosensor applications. Its patented Acyclic Identification of Aptamers (AIA) and multiplexed AIA approaches grew from research and industry partnerships at Syracuse University, with the company applying them to disease detection and its AP3 assay platform. AptaMatrix also developed AlloSwitch sensors for near-real-time detection of biological targets.
Aptar makes the dispensing, dosing and drug-delivery systems that turn everyday packages into usable products, from pharmaceutical devices to beauty pumps and food closures. Headquartered in Crystal Lake, Illinois, the company has spent 80 years developing these technologies and now employs 14,000 people across 20 countries. Its pharmaceutical operation alone includes 18 GMP sites, 120,000 square meters of manufacturing space and capacity for 8 billion systems a year.
With more than 50 years in active material science, Aptar CSP Technologies is an Auburn-based manufacturer serving pharmaceutical and healthcare companies with technologies that help products remain stable and protected. Now transitioning to Aptar Active Material Science, it operates six worldwide locations and supports development through manufacturing under cGMP standards, with ISO-certified facilities and more than 500 employees.
With more than 20 years in digital health, Aptar Digital Health develops regulated software, connected devices, and patient-support platforms that help people manage treatment and help life-sciences partners understand real-world care. As a division of Aptar Pharma, it combines digital-health expertise with Aptar’s drug-delivery capabilities, including connected devices and companion apps such as Migraine Buddy. Its global teams have built more than 40 solutions and work within standards including ISO 13485, ISO 27001, IEC 62304, and MDSAP.