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Founded by cryomedicine researcher John M. Baust, Ph.D., CPSI Biotech is an Owego technology-development company creating investigational cryo-medical devices and life-science research products. Its work combines cryobiology with medical-device engineering for applications in cancer treatment, cardiovascular care, and cell-therapy bioprocessing. CPSI’s pipeline includes more than 10 prototype devices, which it advances toward commercialization through partnerships, licensing, and contract research.
Founded in 1915 by Pennsylvania Dutch farmer and machinist Isaiah G. Engle, CPV Manufacturing makes high-pressure industrial valves and fittings from its facility in Kennett Square, Pennsylvania. The company traces its history from replacement valves for steam-driven pumps to products used in demanding industrial processes and supplied to the U.S. Navy and NASA programs.
Known for patient-centered innovation in clinical care, CQ Medical develops medical devices for radiotherapy and related healthcare settings. Its work includes specialized positioning solutions such as Curvaform for kyphotic patients, while its veterinary oncology efforts support more than 50 clinics across the United States.
CQ Medical develops patient-centric medical devices and positioning solutions for radiotherapy and related clinical care. Its work ranges from specialized supports such as Curvaform for kyphotic patients to systems used in veterinary oncology, where the company partners with more than 50 U.S. clinics. CQ Medical also maintains an external innovation process for ideas intended to improve clinical outcomes or reduce costs.
Family-owned and operated since 1978, CQ Printing is a Strongsville- and Medina-based commercial print shop that takes projects from design through production, mailing, and fulfillment. Its in-house operation handles both offset and short-run digital work, along with finishing and inventory services, giving Northeast Ohio businesses one place to manage printed branding materials. The company also ships nationally.
From its Geneva shop in New York’s Finger Lakes, CQ Sign Company designs, builds and installs custom signage, including carved and wood signs, lighted displays and vehicle graphics. Owner Peter C. Miller’s company also rents billboards and is a member of the Geneva Area Chamber of Commerce.
For more than six decades, CQL Manufacturing has remained at the same Salem, Ohio, location, carrying forward the metal-forming business founded there in 1962. Formed in 2021 through the merger of Compco Quaker Manufacturing and Liberty Steel Industries, CQL serves customers in transportation, agriculture and related manufacturing markets from its 104,000-square-foot facility. The company holds ISO 9001 and IATF 16949:2016 accreditation and was named the Salem Chamber’s 2022 Large Business of the Year.
CR Gibson is a consumer products company within the craft, seasonal, and celebrations markets, primarily engaged in the design, manufacture, procurement, distribution, and sale of all occasion and seasonal social expression products, principally to mass market retailers.
Born in Dr. Kathryn Daltorio’s mechanical engineering lab at Case Western Reserve University, CrabLine Robotics develops crab-like, multi-legged robots for precise work underwater. Its thruster-independent machines use their legs to stabilize on pipes and other structures while delivering tools or retrieving objects in difficult industrial and military environments. The Cleveland company was formed in early 2023 by Daltorio, entrepreneur Carla Macklin, and PhD candidates John Grezmak and Jiyuan Jiang with support from the National Science Foundation.
Crackling Crust Microbakery is a hands-on “microbakery” built around naturally fermented bread and a sense of community. Its baker supports nearby farms when possible and uses eggs from a personal flock of hens called “The Divas,” while sharing the craft through local farmers-market baking and sourdough classes.
Crafco, Inc. manufactures pavement-preservation materials and the equipment used to apply them, serving infrastructure maintenance and rehabilitation needs. Established in 1976, the company says its materials and equipment are manufactured across the United States and distributed worldwide; it is an Ergon company. Its work spans roads, bridges, airports and athletic surfaces.
Founded in 2012 by former Army helicopter mechanic Jan Nawa, Craft Alliance Packaging Solutions (CAPS) is a mobile bottling and packaging-services company serving craft beverage producers from Pennsylvania’s Cumberland Valley. Operating within a four-hour radius, CAPS brings professional bottling support, equipment expertise, and training directly to clients across the Mid-Atlantic.
Craft Cabinetry makes solid-wood kitchen and bath cabinets, pairing Birch construction with dovetail joinery, soft-close hardware, and full-extension drawers. Its collection centers on Shaker and recessed-panel styles, offered as ready-to-assemble cabinets that can ship the next day or as assembled units available within a few business days. The company also supports dealers with online ordering, shipment tracking, and no-hassle replacements.
Craft Cannery is a Bergen, New York contract food manufacturer that turns customer recipes and concepts into shelf-ready sauces, dressings, marinades and other packaged foods. Founded by Paul Guglielmo through his Guglielmo Sauce business, the company combines small-batch production with capacity of up to 2,000 gallons a day, helping emerging food makers move from the kitchen to market without minimum orders. Its FDA-registered, USDA-certified and SQF-certified facility won $500,000 in the 2022 Grow-NY food and agriculture competition, funding expansion and additional regional jobs.
Founded in Brooklyn in the 1990s, Craft For Kids is a family-owned wholesaler and manufacturer of arts, crafts, toys and accessories. Its merchandise now reaches more than 800 stores, supported by a global manufacturing network and an emphasis on broad selection and value.
In Oley, Pennsylvania, Craft Foundry is a one-woman workshop making handmade jewelry, candles poured into upcycled containers, vintage-material cards and creative classes. The studio also thoughtfully curates a small selection from other makers, turning its offerings into a gathering place for handmade goods and shared creativity.
Craft of the Reply is a greeting card movement established in 2020 that designs and produces beautifully crafted, customizable, and inclusive greeting cards, stationery, and paper gifts using recycled, reused, and found paper.
Craft Products Company specializes in water treatment and water analysis regimes, providing economical and analytically accurate programs. With corporate headquarters in Pittsburgh, Pennsylvania, their facility includes manufacturing, blending, warehousing, laboratory, and support functions. They serve customers in Pennsylvania, Ohio, and West Virginia, and are expanding throughout the United States and internationally with a private label product line for water analysis products and services.
Founded by Allen Craft in 1975, Craft Tire supplies used and repaired off-the-road tires while extending casing life through its Shrader Retreading division. After acquiring Shrader Retreading in 2003, the company grew to operate two retread plants and a five-truck service network covering 16 states. Its retreading operation uses the Marangoni-Mammuth system and also handles foam-filled and solid tires.
Craft-Bilt Manufacturing Company is a family-owned manufacturer of outdoor living and architectural products, with more than 80 years of manufacturing history. It makes products for residential outdoor spaces and commercial projects, including aluminum decking and railing. The company’s products are installed by authorized dealers under the Betterliving and Aristocrat brands.