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Since 1942, Cyclotherm of Watertown has built individually configured package steam and hot-water boilers in Watertown, New York, along with marine steam generators and specialized heat-transfer equipment. Its compact two-pass design and patented Cyclonic Combustion define the company’s approach, while more than 26,000 package boilers built and equipment still operating from 1947 speak to its long service history. Cyclotherm also supports more than 10,000 customers with replacement parts and technical assistance.
Founded by beauty expert Cygalle Dias in 2015, Cygalle Beauty makes natural, oxygen-infused skincare centered on full-spectrum phytocannabinoid-rich hemp. The brand grew from Dias’s holistic healing work and the Cygalle Healing Spa, named a top global spa by Vanity Fair in 2009, and its hemp is American-harvested from a Colorado family that has cultivated it for more than three generations. Its skincare ritual pairs hemp with ingredients such as Dead Sea mud and botanical oils in a wellness-focused approach to daily skin care.
Cygnus Automation, Inc. provides U.S.-made electronic systems and PCB assembly for low- to medium-volume production, with work spanning prototype support through testing and delivery. Based in Bohemia, New York, the company combines 25 years of experience with quick-turn production, responsive changes to specifications and schedules, and quality inspection throughout the process. Its capabilities also extend to electro-mechanical, chassis, cable and wiring assembly.
Cygnus Manufacturing Company is a Saxonburg manufacturer known for carrying projects from prototype through production in a 100,000-square-foot climate-controlled facility. It serves OEM customers that need precision-machined components or finished assemblies for demanding medical and aerospace applications. Its quality system is certified to ISO 9001:2015, ISO 13485:2016 and AS9100:D, with ITAR registration.
Cylform Automation Design develops and produces custom forming equipment and turnkey automation for HVAC manufacturers working with thin-wall tubes, starting with flat sheet and processing the complete formed tube. Rather than offering a fixed catalog of machine models, the company draws on a large database of forming concepts to tailor workstations and fully automatic production lines to each customer’s needs. Its engineering and production work is supported by decades of manufacturing experience, while remanufacturing and field-service programs help extend the working life of existing HVAC equipment.
Cylinder Sales and Testing, LLC is a regional cylinder recertification and refurbishment business serving customers who depend on high- and low-pressure gas cylinders. Its Baton Rouge headquarters and Maryland location support a full-service shop that uses automated equipment for testing and refurbishment, helping reduce the downtime associated with taking cylinders out of service.
Since 1958, Gardner-family-owned Cylinders & Valves, Inc. has manufactured small-bore hydraulic cylinders and hydraulic valves from its Strongsville, Ohio, operation. The small Midwest manufacturer stands out for making its products fully serviceable and repairable, while also adapting standard cylinders to customer specifications. It supports that long-running product line with repair services and replacement parts for keeping worn equipment in service.
Founded by scientists from Karolinska Institutet and the Feinstein Institute for Medical Research, Cymbathera AB develops a non-invasive bioelectronic medical device for targeted vagus nerve stimulation to help relieve pain and regulate chronic inflammation. The Lund-based company builds on decades of neuroimmunology research, including Kevin Tracey’s discovery of the inflammatory reflex, and is translating that work into a drug-free approach delivered through the ear’s cymba conchae. Its investigational device remains under clinical and regulatory evaluation.
Cynara is an artichoke specialist that develops, produces and markets artichokes and artichoke foods from a global sourcing network spanning Spain, Peru, Italy and China. Based in Mula, Murcia, the company uses its own research laboratory and an IFS-certified production process to create both traditional preserved hearts and more unexpected formats, including its artichoke snack. Cynara’s year-round focus is on making artichokes more varied and available while reducing environmental impact.
Formed by the 2024 merger of Cynosure and Lutronic, Cynosure Lutronic makes energy-based laser and radiofrequency devices for medical-aesthetic and gynecologic practices. The company combines six decades of product innovation with clinical and manufacturing expertise, and supports practitioners through training, clinical resources, and a service network spanning more than 35 U.S. vans and five warehouses. Its portfolio includes platforms such as the multifrequency XERF radiofrequency system and the Ultra fractional laser.
Founded in 2007, employee-owned Cypress Envirosystems is a San Jose manufacturer known for modernizing aging facilities without shutting them down. Its U.S.-designed Digital Overlay technology adds connectivity to existing equipment in critical settings such as nuclear plants and hospitals, often installing in minutes with minimal disruption. The company designs and manufactures its products at its San Jose factory for customers across North America and Europe.
Founded in 1981 by engineer Harry Turner and his wife, Pamela, Cytec Corp. grew from Harry’s reed-relay designs into a specialist manufacturer of programmable switching systems. Still based in Upstate New York, the company builds standard and custom equipment for automated test and data acquisition, serving customers from small manufacturers to aerospace and defense contractors worldwide. Sales, engineering, and production work together at one location, where Cytec manufactures its products under ISO 9001:2015 certification.
Czarnowski Collective is a brand experience agency founded in Chicago in 1947 as an exhibit house, now operating as four integrated studios offering strategy, creative, fabrication, and technology. The company designs and builds trade show exhibits, events, environments, and temporary structures, with in-house fabrication across six major U.S. production facilities. It serves industries including sports, automotive, manufacturing, and consumer brands, and has worked with clients such as Toyota, Red Bull, and Panasonic.
Since 1938, family-operated Czerw’s Kielbasy has made old-fashioned Polish foods in Philadelphia, with kielbasa still smoked in the brick-oven smokehouses built by founder Jan Czerw. The business continues his recipes and uses natural fruit woods, making its kielbasa fresh daily without artificial fillers or preservatives. Its handmade pierogies and other Polish specialties are also prepared on the premises.
Founded in Mansfield in 1992, D & D Emulsions Inc. manufactures and distributes environmentally sound road-maintenance and dust-control products. The company developed its own trademarked and patented formulations, including Dust Bond for suppressing dust and stabilizing soil, while also serving as a licensed manufacturer and distributor of Golden Bear Oil products. Its products have been distributed across most states east of the Mississippi River.
In business at the same Willoughby location since 1993, D & D Quality Machining produces precision components such as fittings, valve bodies and specialized machined parts for industrial customers. Its 8,000-square-foot air-conditioned facility supports just-in-time and ship-to-stock supply, with warehousing and inventory management built into the service. The company has been ISO 9001-2008 certified since 2002 and specializes in stainless steel machining.
D & M DESAI INC operates in the Personal Care Product Manufacturing industry. The company has 11-50 employees.
3D Agility engineers and 3D-prints replacement parts for equipment sidelined by discontinued components, long lead times, or missing drawings. The Harrisburg company can scan a physical part, reverse-engineer its geometry, and combine additive manufacturing with traditional processes when a printed part alone is not enough. Its work is backed by an ISO 9001:2015-certified quality management system and includes one-off replacements as well as larger runs.
Founded as a packaging broker in 1985, D Bag Lady began manufacturing in 1992 and now produces custom and specialty flexible barrier packaging in Fairport, New York. Its work includes custom-fit pouches and shrouds, with capabilities suited to both one-piece orders and larger production runs. D Bag Lady has been owned and operated by Extra Packaging LLC since 2022.
For more than a decade, 3D Brooklyn LLC has operated as a design studio and 3D printing service, turning sketches and ideas into custom physical objects. Under the sole leadership of Will Haude, the company works especially closely with marketing agencies on branded campaign pieces and promotions, while also handling prototypes, custom components and production runs. Its portable studio can even bring 3D scanning and live printing to branded events, where guests can leave with personalized creations.